Nicotine alters brain development
Authors:
D. Hrubá; A. Peřina
Authors‘ workplace:
Ústav ochrany a podpory zdraví, Lékařská fakulta MU, Brno
přednostka prof. MUDr. Z. Derflerová Brázdová, DrSc.
Published in:
Čes-slov Pediat 2015; 70 (6): 356-360.
Category:
Review
Overview
Exposure to tobacco and especially to nicotine is not only a health problem for adults. It has also been shown to damage the health of the foetuses, newborns, children and adolescents, who are more vulnerable to influence of hazardous factors. The new scientific literature is concerned about understanding to mechanisms of nicotine effects on the onset of cognitive and emotional disturbances, described by many epidemiologic studies for exposed population. Their maturation of neural circuity is not yet completed and the inherent plasticity of the developing brain makes them particularly vulnerable to nicotine-induced alteration. These results arise over the protection of prenatal and postnatal exposure to nicotine as the priority.
Key words:
exposure to nicotine, brain development, foetus, newborn, child, adolescent
Sources
1. Durazzo TC, Mattsson N, Weiner MW. Smoking and increased Alzheimer´s disease risk: a review of potential mechanisms. Alzheimer and Dementia 2014; 10: S122–S145.
2. Abrams DB. Promise and peril of e-cigarettes. Can disruptive technology make cigarettes absolete? JAMA 2014; 311: 135–136.
3. Gornale J. Why e-cigarettes are dividing the public health community? BMJ 2015; 24: 350:U3317.
4. Mangan D. E-cigarette sales are smoking hot, set to hit $ 1.7 billion. CNBC Healthcare [on-line]. August 28, 2013 [cit. 4. 9. 2015]. Dostupné z: .
5. England LJ, Bunnell RE, Pechacek TF, et al. Nicotine and the developing human. A neclected element in the electronic cigarette debate. Am J Prev Med 2015; 49: 286–293.
6. Albuquerque EC, Pereira EFR, Alkondon M, Rogers SW. Mammalian nicotine acetrylcholine receptors. From structure to function. Physiol Rev 2009; 89: 73–120.
7. Wessler I, Kilpatric CI. Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br J Pharmacol 2008; 154: 1558–1571.
8. Julvez J, Ribas-Fitó N, Torrent M, Forns M. Maternal smoking habits and cognitive development of children at age 4 years in a population-based birth cohort. Int J Epidemiol 2007; 36: 825–832.
9. Bowker K, Lewis S, Coleman T, Cooper S. Changes in the rate of nicotine metabolism across pregnancy: a longitudinal study. Addiction 2015, June 22; doi 10.1111/add.1 3029 [Epub ahead of print].
10. Dwyer JD, Beside RS, Leslie FM.. Nicotine and the brain development. Birth Defects Res C Embryo Today 2008; 84: 30–44.
11. Moon RY, Liu C, Bishop R, et al. Sudden infant death syndrome. Lancet 2007; 370: 1578–1587.
12. Dwyer JD, McOuown SC, Leslie FM. The dynamic effects of nicotine on the feveloping brain. Pharmacol Ther 2009; 122: 125–139.
13. Ekblad M, Korkeila J, Parkkola R, et al. Maternal smoking during pregnancy and regional brain volumes in preterm infants. J Pediatr 2010; 156: 185–190.
14. Cents RAM, Tiemeier H, Velders FP, et al. Maternal smking during pregnancy and child emotional problems: The relevance of maternal and child 5-HTTLPR genotype. Am J Med Genet B Neuropsychiatr Genet 2012; 159B: 289–297.
15. Berlin I, Heilbronner C, Georgieu S, et al. Reduced monoamine oxidase A activity in pregnant smokers and their newborns. Biol Psychiatry 2009; 66: 728–733.
16. Hrubá D. Riziko kouření v těhotenství se stále podceňuje. Prakt Gyn 2011; 15: 1–2.
17. US DHHS. The health concequences of smoking: 50 years of progress. A report of the Surgeon General. [online] Atlanta, GA. US DHHS CDC, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. 2014 [cit. 4. 9. 2015] Dostupné z: http://www.ncbi.nlm.nih.gov/books/NBK179276/pdf/Bookshelf_NBK179276.pdf.
18. Slotkin TA. If nicotine is a developmental neurotoxicant in animals, do we recommend nicotine replacement therapy in pregnant women and adolescents? Neurotoxicol Terratol 2008; 30: 1–19.
19. American College of Obstetricians and Gynecologists. Tobacco use and women health. Committee Opinion No. 503. Obstet Gynecol 2011; 118: 746–750.
20. Leung Ch.Y, Leung GM, Schooling CM. Early second-hand smoke exposure and child and adolescent mental health: evidence from Hong Kong´s children of 1997´birth cohort. Addiction 2015; doi: 10.1111/add.1 3033 [Epub ahead of print].
21. Chen R, Clifford A, Lang L, Anstey KH. Is exposure to secondhand smoke associated with cognitive parameters of children and adolescents? A systematic literature review. An Epidemiol 2013; 23: 652–661.
22. Holleisten T, Lougheed JP. Beyond storm and stress. Typically, transactions, timing and temperament to account for adolescent change. Am Psychol 2013; 64: 444–454.
23. CaseyB, Jones RM, Somerville LH. Breaking and accelerating of the adolescent brain. J Res Adolesc 2011; 1: 21–33.
24. Goriunova NA, Mansvelder HD. Nicotine exposure during adolescence alters rules for prefrontal cortical synaptic plasticity during adulthood. Frontiers in Synaptic Neurosci 2012; 32: 10484–10493.
25. Yuan M, Cross SJ, Loughlin SE, Leslie FM. Nicotine and the adolescent brain. J Physiol 2015; 593: 3397–3412.
26. Naneix F, Marchand AR, DiScala G, et al. Parallel maturation of goal-directed behavior and dopaminergic systems during adolescence. J Neurosci 2012; 32: 16223–16232.
27. Gotti C, Zoli M, Clementi F. Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends Pharmacol Sci 2006; 27: 482–491.
28. Shram MJ, Siu EC, Li Z, et al. Interactions between age and the aversive effects on cotinine withdrawal under mecymylamine-precipitated and spontaneous conditions in male Wistar rats. Psychopharmacology (Berl) 2008; 198: 181–190.
29. Dao JM, McQuown SC, Loughlin SE, et al. Nicotine alters limbic function in adolescent rat by a 5-HT receptor mechanisms. Neuropsychopharmacology 2011; 36: 1319–1331.
30. Slotkin TA, Seidler FJ. Nicotine exposure in adolescence alters the response of serotonin systems to nicotine administered subsequently in adulthood. Dev Neurosci 2008; 31: 58–70.
31. Kendler KS, Myers J, Damaj MJ, Chen X. Early smoking onset and risk for subsequent nicotine dependence: A monozygotic co-twin control study. Am J Psychiatry 2014; 170: 408–413.
32. Gartner C, Hall W. A licence to vape: Is it time to trial on a nicotine licencing scheme to allow Australian adults controlled access to electronic cigarettes devices and refill solutions containing nicotine? Int J Drug Policy 2015; 26: 548–553.
33. Goniewicz ML, Zielinska-Danch W. Electronic cigarette use among teenagers and young adults in Poland. Pediatrics 2012;130: e870–e885.
34. Grana R, Benowitz N, Glantz SA. E-cigarettes. A scientific review. Circulation 2014; 129. 1972–1986.
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2015 Issue 6
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