Endothelial Dysfunction

Czech version

Authors: M. Mráz ¹; P. Spurný ²; M. Pytliak ³; Ľ. Podracká ¹
Authors‘ workplace: Klinika detí a dorastu LF UPJŠ, Košice1 prednostka prof. MUDr. Ľ. Podracká, CSc. Kardiologické oddelenie, Východoslovenský ústav srdcových chorôb, Košice2 primár MUDr. M. Studenčan, PhD. Interná klinika LF UPJŠ a FNsP, Košice3 prednostka prof. MUDr. I. La
Published in: Čes-slov Pediat 2004; (6): 311-315.
Category:

Overview

In the last two decades, there is a radical change in the approach to the vascular endothelium. Nowadays, it isnot only the monolayer of cells, as thought 20 years ago, but also the largest human endocrine organ with crucialrole inmaintaining vascular homeostasis. Dysfunction of endothelial cells as seen in hypertension, diabetes mellitus,hyperlipidemia or smoking is the first, but reversible step in atherogenesis. Hence, early diagnosis and treatmentof endothelial dysfunction may lead to decreasing of cardiovascular morbidity and mortality in the population.

Key words:
endothelium, atherosclerosis, prevention

Full text is not available online.

If interested in a scan of this journal, contact NTO ČLS JEP.