Apremilast in the Treatment of Ulcerations in Possible Non-uremic Calciphylaxis. Case report
Authors:
H. Kristlová 1,3; J. Bočková 1; J. Horažďovský 1; M. Kadlecová 1; H. Kořínková 1; A. Rosolová 1; M. Pešková 2; M. Rendlová 3
Authors‘ workplace:
Kožní oddělení, Nemocnice České Budějovice, primář MUDr. Jiří Horažďovský, Ph. D.
1; Interní oddělení, Nemocnice České Budějovice, primář MUDr. Marie Pešková
2; Dermatovenerologie Rendlová s. r. o., České Budějovice
3
Published in:
Čes-slov Derm, 96, 2021, No. 3, p. 142-148
Category:
Case interpretation
Overview
The authors report a case of a 55-year-old woman, who has been developing deep ulcers on the trunk and limbs for 5 years. They were based on non-uremic calciphylaxis and extended to the total area of 988 cm2. Treatment with corticosteroids and azathioprine was not successful, the administration of apremilast led to healing of 97% of the ulcers. Apremilast could represent a new alternative in the treatment of this disease.
Keywords:
pyoderma gangrenosum – non-uremic calciphylaxis – immunosuppression – apremilast
Sources
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Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
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