Multiple Rough Papules with Positive Auspitz’s Sign – Morbus Flegel. Minireview.
Authors:
M. Důra 1; O. Kodet 1,2,3; M. Petráčková 1; J. Štork 1
Authors‘ workplace:
Dermatovenerologická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. Jiří Štork, CSc.
1; Anatomický ústav 1. LF UK, přednosta prof. MUDr. Karel Smetana, DrSc.
2; BIOCEV – Biotechnologické a biomedicínské centrum Akademie věd a Univerzity Karlovy ve Vestci u Prahy, vedoucí laboratoře prof. MUDr. Karel Smetana, DrSc.
3
Published in:
Čes-slov Derm, 96, 2021, No. 3, p. 150-152
Category:
Overview
The authors report a case of a 65-year-old woman with nine month history of cutaneous lesions that subsided temporarily after the administration of topical corticosteroids. The biopsy confirmed a typical signs of hyperkeratosis lenticularis perstans – morbus Flegel. An incidental finding was a significant pitting of the fingernails, which with the current positivity of the Auspitz sign might lead to the diagnosis of psoriasis. The coincidence of nail changes and morbus Flegel has not been described yet. The paper provides an overview of current knowledge of this rare disease
Keywords:
hyperkeratosis lenticularis perstans – morbus Flegel – nail pitting
Sources
1. BOLOGNIA, J., JORIZZO, JL., SCHAFFER, JV. Dermatology. 3rd Edition. Philadelphia: Elsevier/Saunders, 2012, 2 vol., p. 1803–1804. ISBN 978-0723435716.
2. BORTOLUZZI, P., CUSINI, M., VERALDI, S. et al. Hyperkeratosis lenticularis perstans (Flegel‘s disease): our experience and review of the literature. Int J Dermatol, 2021, 60(1), p. 33–38.
3. CALONJE, E., BRENN, T., LAZAR, AJ. et al. McKee‘s Pathology of the Skin. 5th Edition. Amsterdam: Elsevier/Saunders, 2019, 2 vol., p. 110. ISBN 978-0-7020-6983-3.
4. ERRICHETTI, E., TURINA, M., PIZZOLITTO, S. et al. Dermoscopy of hyperkeratosis lenticularis perstans (Flegel disease). J Dermatol, 2019, 46(8), e298–e299.
5. FLEGEL, H. Hyperkeratosis lenticularis perstans. Hautarzt, 1958, 9(8), p. 363–364.
6. OZBAGCIVAN, O., LEBE, B., FETIL, E. Dermoscopic pattern of Kyrle‘s disease. An Bras Dermatol, 2020, 95(2), p. 244–246.
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2021 Issue 3
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