Levosimendan and renal function
Authors:
F. Málek; P. Ošťádal; A. Krüger; D. Vondráková; J. Matoušková; P. Neužil
Authors‘ workplace:
Kardiovaskulární centrum
; Nemocnice Na Homolce, Praha
; Ambulance srdečního selhání a hypertenze
Published in:
Kardiol Rev Int Med 2013, 15(3): 178-180
Category:
Overview
Decreased renal function is usually observed in patients with heart failure, the impaired kidney functions have a negative impact on the outcome and renal dysfunction is a limiting factor for the effect of optimal medical therapy. A short‑term renoprotective effect of Levosimendan was shown in hemodynamic studies. Other studies confirmed that the positive effect of Levosimendan on the kidney function is long‑term. This effect is explained by several mechanisms of action; besides redistribution of renal blood flow, Levosimendan also has an anti‑inflammatory effect.
Keywords:
heart failure – Levosimendan – renal function
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Labels
Paediatric cardiology Internal medicine Cardiac surgery CardiologyArticle was published in
Cardiology Review
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