Pathophysiology of cardiorenal syndrome
Authors:
F. Málek
Published in:
Kardiol Rev Int Med 2012, 14(4): 233-236
Category:
Overview
Cardiorenal syndrome is defined as a state, when each dysfunctional organ – heart or kidney – has the ability to initiate and perpetuate disease in the other organ through common hemodynamic, neurohormonal, immunological and biochemical feedback pathways. In the pathophysiology of cardiorenal syndrome, several factors play role: decreased cardiac output associated with increased renal vein and intrabdominal pressure, lack of renin-angiotensin-aldosteron system inhibition, renal sympathetic nerve activation in arteries, oxidative stress, anemia and erythropoetin underproduction and others.
Keywords:
cardiorenal syndrome – heart failure – renal dysfunction – patophysiology
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Cardiology Review
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