Physical activity in patients with Crohn‘s disease and ulcerative colitis
Authors:
Líška D.
Authors‘ workplace:
Katedra telesnej výchovy a športu, Filozofická fakulta, Univerzita Mateja Bela v Banskej Bystrici, Slovenská republika
Published in:
Rehabil. fyz. Lék., 29, 2022, No. 4, pp. 169-173.
Category:
Original Papers
doi:
https://doi.org/10.48095/ccrhfl2022169
Overview
Crohn’s disease and ulcerative colitis belong to a heterogeneous group of diseases classified as inflammatory bowel disease. The etiopathogenesis of the disease involves multifactorial causes of which the genetic predisposition, interstitial microbiome, abnormal immune response and environmental factors play a significant role. Physical exercise can be used as potential therapy. Exercise may increase expression of interleukin-6 (IL-6) and the anti-inflammatory cytokine IL-10. Exercise can also lead to alleviation of stress-induced intestinal barrier dysfunction and relieves symptoms of disease. Physical activity at adequate doses decreases visceral fat and results in the release of pro-inflammatory cytokines and myokines such as IL-6. Regular exercise is associated with autophagy, which is associated with intracellular degradation with a protective effect before the disease develops. Another possible mechanism induced by exercise is to affect the tumour necrosis factor alpha. Exercise can also potentiate the effect of ameliorating symptoms by means of the heat shock protein. Exercise can prevent non-specific intestinal inflammation and reduces the risk of relapse. Regular exercise also contributes to optimal patient body composition and enhances the quality of life of patients with non-specific intestinal inflammation.
Keywords:
Physical activity – Ulcerative colitis – Crohn’s disease – rehabilitation
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Physiotherapist, university degree Rehabilitation Sports medicineArticle was published in
Rehabilitation and Physical Medicine
2022 Issue 4
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