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Immunosuppression Following Venous Allografts Transplantations – The Authors’ experience


Authors: M. Adamec;  I. Matia;  L. Janoušek
Authors‘ workplace: KTCH IKEM Praha, přednosta: prof. MUDr. Miloš Adamec, CSc.
Published in: Rozhl. Chir., 2011, roč. 90, č. 2, s. 130-133.
Category: Monothematic special - Original

Overview

Aim:
Venous and arterial graft usage in vascular reconstructions was re-discovered in connection with organ transplantation development. Allografts are employed in many clinics, however, uniform opinion on the use of immunosuppression after the procedure of venous graft transfer from a cadaveric donor, is still lacking.

Material and Methods:
The authors present their own group of patients who underwent vascular reconstructions, and in whom allogenic vein was used. The majority of indications for bypass procedures resulted from critical limb ischemia. Immunosuppressive medication was administered during the vascular procedure and, over the past several years, it purely consisted of tacrolimus monotherapy.

Results:
In the group of 101 patients, no serious complications due to adverse effects of immunosuppresion therapy were recorded.

Key words:
immunosuppression – venous allograft – transplantation – critical limb ischemia


Sources

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Surgery Orthopaedics Trauma surgery
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