Statins and liver

Czech version

Authors: Jiří Hlušička ¹; Mahak Arora ²; Radan Brůha ¹; Aleš Žák ¹
Authors‘ workplace: 4. interní klinika – klinika gastroenterologie a hepatologie 1. LF UK a VFN v Praze ¹; Farmakologický ústav 1. LF UK a VFN v Praze ²
Published in: Čas. Lék. čes. 2022; 161: 80-83
Category: Review Article

Overview

Statins are widely accepted hypolipidemics that work by inhibiting hydroxymethylglutaryl coenzyme A reductase and thereby inhibiting cholesterol synthesis. They significantly reduce cardiovascular risk. Their use could be associated with side effects, which are serious only in rare cases. However, an unhealthy lifestyle, obesity, and elevation of blood lipids do not only damage the cardiovascular system. The current topic not only in hepatology is non-alcoholic fatty liver disease – NAFLD. The aim of this article is, among others, to draw attention to the pleiotropic effects of statins, which could be used in the treatment of this disease in the future. Recent studies have suggested that the administration of statins to patients with NAFLD is beneficial.

Keywords:

NAFLD – statins – hepatopathy

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Labels

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

ÚVODEM

EDITORIAL

Liver tests

Diagnostic methods of fatty liver diseases

Liver elastography

Metabolic dysfunction-associated fatty liver disease (MAFLD) as a more accurate name for NAFLD – common aspects of pathogenesis

Diagnosis of non-alcoholic fatty liver disease and its active screening in risk groups

An overview of current therapy options of non-alcoholic fatty liver disease

Current hepatitis C therapy

Klinická obezitologie – nejen Základy

Dietary habits in students from the medical faculties

Za profesorem Peterem Krištúfkem, čestným prezidentem SLS

Article was published in

Journal of Czech Physicians

2022 Issue 2