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Bartter’s Syndrome – Hypokalemic Renal Tubular Syndrome


Authors: K. Gazdíková;  F. Gazdík
Authors‘ workplace: Klinika farmakoterapie Ústavu preventívnej a klinickej medicíny, Bratislava
Published in: Čas. Lék. čes. 2003; : 474-478
Category:

Overview

Hypokalemia is associated with some renal diseases manifested by renal tubular acidosis (type I and II) or by renaltubular syndrome (Bartter’s, Gitelman’s and Liddle’s syndrome). Bartter’s syndrome, originally described by Batterand colleagues in 1962, is a set of closely related renal tubular disorders characterized by hypokalemia, hypochloremia,metabolic alkalosis and hyperreninemia with normal blood pressure. The underlying renal abnormality resultsin excessive urinary losses of sodium, chloride, potassium and calcium. Muscle weakness, polydipsia, polyuria andmental retardation can be also present. Affected children have poor growth rates and they appear malnourished. Thearticle is focused on ethiopathogenesis, laboratory and clinical characteristics and on the treatment of Bartter’ssyndrome.

Key words:
Bartter’s syndrome, hypocalemic renal tubular syndrome, hypokalemia, metabolic alkalosis.

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Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

Article was published in

Journal of Czech Physicians


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