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Helicobacter pylori and Diabetes mellitus


Authors: J. Zelenková;  A. Součková 1;  M. Kvapil;  A. Souček 2;  J. Vejvalka 3;  J. Segethová
Authors‘ workplace: Interní klinika 2. LF UK a FNM, Praha 1Ústav mikrobiologie a imunologie 2. LF UK, Praha 2Ústav lékařské mikrobiologie a imunologie 1. LF UK, Praha 3Oddělení aplikované informatiky 2. LF UK, Praha
Published in: Čas. Lék. čes. 2002; : 575-577
Category:

Overview

Background.
Helicobacter (H.) pylori participates significantly on the pathogeny of chronic gastritis, duodenala gastric ulcer, carcinoma and lymphoma of the stomach. Attention was attracted also by some extragastric diseases,including diabetes mellitus, where the elevated antibodies levels against H. pylori was found. The aim of the workwas to determine the seroprevalence in relation to the sex and type of disease in a cohort of diabetics and in a controlgroup of blood donors.Methods and Results. In 195 diabetic patients (type I and II) and 216 blood donors levels of IgG antibodies weredetermined by ELISA method. Seroprevalence in the group of diabetic patients was 27 %, in males 26 % and inwomen 28 % (n.s.). No differences related to sex or diabetes type were found. Significant differences in seroprevalencewere found among the group of diabetic patients and blood donors (27 % vs. 51 %, p

Key words:
Helicobacter pylori, seroprevalence, diabetes mellitus.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist
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