Sentinel lymph node in malignant melanoma

Czech version

Authors: Eva Rovenská
Authors‘ workplace: Klinika chirurgickej onkológie Slovenskej zdravotníckej univerzity a Národného onkologického ústavu Bratislava, Slovenská republika, prednosta prof. MUDr. Juraj Pechan, CSc.
Published in: Vnitř Lék 2014; 60(5-6): 484-489
Category: Review

Overview

Melanoma is highly malignant tumor which arises through malignant transformation of melanocytes. Surgical treatment of primary cutaneous melanoma including radical excision and intervention in regional lymphatic drainage is irreplaceable. Sentinel node biopsy is a recognized method of defining the stage of disease. Performance of sentinel node biopsy in patients in clinical stage Ib and II may reveal clinically occult nodal disease and thereby help identify a group of patients with occult stage III disease who may thereafter undergo complete lymphadenectomy and systemic treatment. Sentinel node biopsy is beneficial in treatment of melanoma, but the therapeutic value of sentinel node biopsy is still not completely clear and remains disputable.

Key words:
melanoma – sentinel lymph node – sentinel node biopsy

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