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The prophylaxis and treatment of antiphospholipid syndrome – current options, difficulties and future perspectives


Authors: A. Buliková 1,2;  P. Smejkal 1,2;  J. Kissová 1,2;  G. Chlupová 1;  M. Matýšková 1;  M. Šlechtová 1
Authors‘ workplace: Oddělení klinické hematologie FN Brno, přednosta prof. MUDr. Miroslav Penka, CSc. 1;  Lékařská fakulta MU Brno, děkan prof. MUDr. Jiří Mayer, CSc. 2
Published in: Vnitř Lék 2012; 58(7 a 8): 110-122
Category: 60th Birthday prof. MUDr. Miroslav Penka, CSc.

Overview

The antiphospholipid syndrome is the most frequent acquired thrombophilia. However, not only thromboembolic events belong to possible clinical manifestations which are caused by antiphospholid antibodies presence. Patients could also suffer from pregnancy loss and/or wide spectrum of non-thromboembolic complications. The paper summarizes current treatment options and recommendations, their difficulties and brings new visions for the future.

Key words:
antiphospholipid syndrome – prophylaxis – treatment – perspectives


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