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Effect of ivabradin on heart rate, left ventricular function a NT-proBNP concentration in patients with systolic chronic heart failure – case reports


Authors: F. Málek
Authors‘ workplace: Kardiovaskulární centrum Nemocnice Na Homolce Praha, přednosta prim. MUDr. Štěpán Černý, CSc.
Published in: Vnitř Lék 2012; 58(10): 779-783
Category: Case Reports

Overview

Ivabradin is indicated in patients with compensated chronic heart failure and sinus rhythm with resting heart rate ≥ 75 beats per minute despite maximal tolerated beta-blocker dose. Three case reports show favourable effect of ivabradin therapy on heart rate, reverse cardiac remodeling and B-type natriuretic peptide concentration in patients with systolic heart failure.

Key words:
chronic heart failure – ivabradin – heart rate – cardiac remodeling – B-type natriuretic peptide


Sources

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6. Tardif JC, O’Meara E, Komajda M et al. Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy. Eur Heart J 2011; 32: 2507–2515.

7. Špinar J, Vítovec J, Hradec J et al. Doporučení pro diagnostiku a léčbu chronického srdečního selhání České kardiologické společnosti 2011. Vnitř Lék 2012; 58 (Suppl 1): 1S4–1S40.

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Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 10

2012 Issue 10

Most read in this issue
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