Extrinsic allergic alveolitis – rarely diagnoticated disease

Czech version

Authors: D. Lauková; I. Marget; J. Plutinský
Authors‘ workplace: II. oddelenie pneumológie a ftizeológie Špecializovanej nemocnice sv. Svorada Zobor, n. o., Nitra, Slovenská republika, prednosta doc. MUDr. Ján Plutinský, CSc.
Published in: Vnitř Lék 2009; 55(5): 489-500
Category: Reviews

Overview

Extrinsic allergic alveolitis (EAA), known as hypersensitive pneumonitis, causes interstitial lung involvement by inhaled antigen. The clinical presentation of the disease has been defined as acute, subacute and chronic. The most often symptoms of the acute form of the disease are flu‑like symptoms, dyspnoe and cough. The progressive dyspnoe in particullary is characterized for the chronic form of EAA. Dyspnoe is worsed, if the disease is combinied with usual respiratory infection or reexposition of inhaled antigen. It seems the diagnostic definition of EAA should be easy and prevalence of EAA relative high. The disease belongs to the group of interstitial lung diseases and it is underestimated as a matter of fact. The clinic, radiographic, laboratory and histologic abnormalities are results of inhaled antigen contact and support the diagnosis of EAA. Specific IgG antibodies against the offending antigen along with them are consedered to be detected (established) of EAA.

Key words:
extrinsic allergic alveolitis – forms of EAA – clinic symptoms – diagnostic methods – treatment

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