Peptic ulcer disease and Helicobacter pylori infection in the elderly
Authors:
R. Kroupa
Published in:
Geriatrie a Gerontologie 2015, 4, č. 4: 177-180
Category:
Review Article
Overview
Peptic ulcer disease and its complications are significant health problems among the elderly. Despite the decreasing prevalence of Helicobacter pylori infection in population, the incidence of ulcers and bleeding is stable. The reason may be in a broad use of potentially risky drugs and comorbidities. The diagnosis and treatment of Helicobacter pylori infection is indicated in peptic ulcers, gastric intestinal metaplasia and atrophy, in relatives to persons with gastric cancer and in other situations. Eradication antibiotic therapy should be considered carefully in view of risk and benefit particularly in the elderly.
Keywords:
peptic ulcer – Helicobacter pylori – antibiotics – gastritis - elderly
Sources
1. Marshall B, Warren J. Unidentified curver bacili in the stomachs of patiens with gastritis and peptic ulcer. Lancet 1984; 1: 1311–1315.
2. Malfertheiner P., Chan FKL, McColl KEL. Peptic ulcer disease. Lancet 2009; 374: 1449–1461.
3. Kroupa R, Dítě P, Münzová H, a kol. Changes in incidence of peptic ulcers and gastric cancer in region of the Czech Republic – South Moravia in 1996–2000. Gastroenterologia Polska 2003; 10(2): 115–119.
4. Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal antiinflammatory drugs. Lancet 1994; 343: 769–772.
5. Sierra MS, Hastings EV, Garcia KF, et al. Epidemiology, transmission and public health implications of Helicobacter pylori Infection in western countries. In: Helicobacter pylori, A Worldwide Perspective 2014; 25–79, look, Bethamscience.
6. Goh KL, Chan WK, Shiota S, Yamaoka Y. Epidemiology of Helicobacter pylori infection and public health implications. Helicobacter 2011; 16(Suppl 1): 1–9.
7. Bureš J, Kopáčová M, Koupil I a kol. Significant decrease in prevalence of Helicobacter pylori in the Czech Republic. World J Gastroenterol 2012; 18(32): 4412–4418.
8. Sýkora J, Siala K, Varvarovská J a kol. Epidemiology of Helicobacter pylori infection in asymptomatic children: a prospective population-based study from the Czech Republic. Application of a monoclonal-based antigen-in-stool enzyme immunoassay. Helicobacter 2009; 14: 286–297.
9. Prónai L, Schandl L, Orosz Z. Lower prevalence of Helicobacter pylori infection in patients with inflammatory bowel disease but not with chronic obstructive pulmonary disease – antibiotic use in the history does not play a significant role. Helicobacter 2004; 9: 278–283.
10. Dušek L, Mužík J, Pavlík T a kol. Epidemiologie zhoubných nádorů trávicího traktu v České republice – současný stav a predikce. Gastroent Hepatol 2012; 66(5): 331–339.
11. Brown L. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev 2000; 22: 283–297.
12. Dinis-Ribeiro M, et al. Management of precancerous conditions and lesions in the stomach: guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED). Endoscopy 2012; 44: 74–94.
13. Ford AC, Forman D, Hunt R, et al. Helicobacter pylori eradication for the prevention of gastric neoplasia. Cochrane Database Syst Rev 2015; Jul 22; 7: CD005583
14. Potamitis GS, Axon AT. Helicobacter pylori and Nonmalignant Diseases. Helicobacter 2015; 20(Suppl 1): 26–29.
15. Testerman TL, Morris J. Beyond the stomach: An updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment. World J Gastroenterol 2014; 20(36): 12781–12808.
16. Malfertheiner P, Megraud F, O’Morain CA, et al. Management of Helicobacter pylori infection – the Maastricht IV/ Florence Consensus Report. Gut 2012; 61: 646–664.
17. Seifert B, Dítě P, Bureš J a kol. Gastroenterologie. Doporučení diagnostické a terapeutické postupy pro všeobecné praktické lékaře. Novelizace 2012. Praha: Společnost všeobecného lékařství 2012.
18. Liou JM, Lin JT, Lee CY, et al. Helicobacter pylori infection in the elderly. International Journal of Gerontology 2008; 2(4): 145–153.
Labels
Geriatrics General practitioner for adults Orthopaedic prostheticsArticle was published in
Geriatrics and Gerontology
2015 Issue 4
Most read in this issue
- Fever as a frequent symptome
- Diarrhoeal diseases in general practitioner’s work
- Streptococcal and pneumococcal infections from the geriatrist´s view
- Treatment of non-healing wounds at geriatric patiens