Primary prevention of cancer
Authors:
P. Klener
Authors‘ workplace:
Přednosta: prof. MUDr. Marek Trněný, CSc.
; 1. interní klinika 1. LF, VFN a ÚHKT, Praha
Published in:
Prakt. Lék. 2011; 91(9): 512-516
Category:
Reviews
Overview
Stadily worldwide increasing incidence of cancer should be a stimuli to preventive measures, which could significantly reduce cancer rates. Primary prevention of cancer involves firstly identifying factors associated with the development of the disease. Those risk factors are shortly reviewed. Primary prevention could be oriented to environmental and occupational factors, or to implementation of protective measures into practice. Among self-inflicted measures belongs
- cessation of smoking,
- reduced alcohol consumption,
- stop overnutrition, or
- stop unhealthy dietary habits.
Certain role play the protective substances from the food. Diet rich in fruits and vegetable protects against cancer thanks to different mechnisms, mainly through antioxidative potency of natural compounds such as
- luteolin,
- resveratrol,
- lycopene and others.
Chemopreventive effect has been confirmed also from another substances, such as
- retinoids,
- non-steroid antirevmatics,
- antihormons,
- deltanoids, and
- inhibitors of alfa reductase.
All these are described in detail.
Key words:
cancer, primary prevention, risk factors, protective factors, chemoprevention.
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