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Progressive heart failure due to cardiac amyloidosis


Authors: A. Mikulova;  R. Toušek;  Š. Šindelářová;  A. Kovařík;  K. Lukáčová 1;  J. Kautzner 2
Authors‘ workplace: Kardiocentrum - kardiologie, Nemocnice České Budějovice, a. s. Primář: MUDr. František Toušek, FESC. ;  Oddělení patologie, Nemocnice České Budějovice, a. s. Primářka: MUDr. Jana Přádná 1;  Klinika kardiologie, Institut klinické a experimentální medicíny, Praha Přednosta: Prof. MUDr. Josef Kautzner, CSc, FESC 2
Published in: Prakt. Lék. 2007; 87(10): 628-631
Category: Case Report

Overview

The authors present the case of a 60year old female with a short history of dyspnoea, hospitalised for predominant right heart failure. Based on echocardiographic pattern of restrictive cardiomyopathy and the clinical picture, cardiac amyloidosis was suspected. However, no laboratory tests or other supporting examinations, including liver and greater omentum biopsy, led to the correct diagnosis. The unanimous diagnosis of primary amyloidosis was established by means of endomyocardial biopsy. Due to the fast progression of heart failure any further therapeutic possibilities were limited. In order to consider causal treatment of this disease, endomyocardial biopsy should be performed early, once cardiac amyloidosis is suspected.

Key words:
heart failure, cardiac amyloidosis, echocardiography, endomyocardial biopsy.


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