Idiopathic intestinal infl ammation and autoimmune pancreatitis

Czech version

Authors: T. Kupka ^1,2; P. Dítě ^1,3; D. Solil ³; M. Bojková ^1,2; J. Dolina ³; B. Kianička ⁴
Authors‘ workplace: Lékařská fakulta OU, Ostrava ¹; Interní a kardiologická klinika, FN Ostrava ²; Interní gastroenterologická klinika LF MU a FN Brno ³; II. interní klinika LF MU a FN U sv. Anny v Brně ⁴
Published in: Gastroent Hepatol 2024; 78(5): 409-413
Category:
doi: https://doi.org/10.48095/ccgh2024409

Overview

Autoimmune pancreatitis is a subtype of chronic pancreatitis. Currently, type 1 is known (LPSP – lymphoplasmacytic sclerosing pancreatitis), which is classified among the clinical forms of a group of diseases designated as IgG4-related disease. This form occurs in younger individuals and IgG4 levels are normal with a few exceptions. This type is accompanied in 20–30% via findings of inflammatory bowel diseases, mainly ulcerative colitis. Type 3 autoimmune pancreatitis has been described, but it is still debated. The number of persons with inflammatory bowel diseases and the finding of type 2 autoimmune pancreatitis is highest in persons with ulcerative colitis – up to 2/3 of all patients. In the Mayo Clinic study, 19 persons with inflammatory bowel disease were found in a group of 43 patients with type 2 AIP; similarly, a Japanese study found AIP in 11 cases in a group of 52 patients with inflammatory bowel disease. Other studies have shown similar results. Inflammatory bowel disease with autoimmune pancreatitis is diagnosed in 20% of cases and steroid therapy is usually successful

Keywords:

inflammatory bowel disease – autoimmune pancreatitis type 1 – autoimmune pancreatitis type 2

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Podíl prvého a druhého autora na primoautorství je ekvivalentní.

ORCID autorů

T. Kupka 0000-0001-5510-8498,

P. Dítě 0000-0002-0086-5421,

D. Solil 0009-0004-3343-3424,

M. Bojková 0000-0001-7799-2827,

J. Dolina 0000-0002-9061-5273,

B. Kianička 0000-0003-0988-5928.

Doručeno/Submitted: 22. 7. 2024

Přijato/Accepted: 23. 9. 2024

Korespondenční autor

prof. MUDr. Petr Dítě, DrSc.