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Specifics of hypoglycemia in the geriatric population


Authors: Eva Rajnohová
Authors‘ workplace: Klinika geriatrie LF SZU a UNB, Nemocnica Ružinov, Bratislava
Published in: Forum Diab 2024; 13(3): 133-137
Category: Review Article

Overview

Hypoglycemia in elderly is associated with significant morbidities leading to both physical and cognitive dysfunction. Repeated hospital admissions due to frequent hypoglycemia are also associated with further deterioration in patients’ general health. This negative impact of hypoglycemia is likely to eventually lead to frailty and disability. It appears that the relationship between hypoglycemia and frailty is bidirectional and mediated through a series of influences including under nutrition. Therefore, attention should be paid to the management of under nutrition in the general elderly population by improving energy intake and maintaining muscle mass. Increasing physical activity and having a more conservative approach to glycemic targets in frail geriatric patients with diabetes may be worthwhile.

Keywords:

hypoglycemia – frailty – geriatric patients


Sources

Institute for Health Metrics and Evaluation. GHDx: GBD results tool (2018). Dostupné z WWW: <http://ghdx.healthdata.org/gbd-results-tool>.

Hanlon P, Fauré I, Corcoran N et al. Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. Lancet Healthy Longev 2020; 1(3): e106–116. Dostupné z DOI: <http://dx.doi.org/10.1016/S2666–7568(20)30014–3>.

Yoon SJ, Kim KI. Frailty and disability in diabetes. Ann Geriatr Med Res 2019; 23(4): 165–169. Dostupné z DOI: <http://dx.doi.org/10.4235/agmr.19.0036>.

Holmerová I, Jurašková B, Zikmundová K. Vybrané kapitoly z gerontologie. 2nd ed. Gema: Praha 2007. ISBN 978–80–254–0179–8.

Davies B, García F, Ara I et al. Relationship between sarcopenia and frailty in the Toledo study of healthy aging: A population based cross sectional study. J Am Med Dir Assoc 2018; 19(4): 282–286. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jamda.2017.09.014>.

Kalyani RR, Corriere M, Ferrucci L. Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. Lancet Diabetes Endocrinol 2014; 2(10): 819–829. Dostupné z DOI: <http://dx.doi.org/10.1016/S2213–8587(14)70034–8> .

Rolland Y, Czerwinski S, Abellan Van Kan G et al. Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J Nutr Health Aging 2008; 12(7): 433–450. <http://dx.doi.org/10.1007/BF02982704>.

Keegan GL, Bhardwaj N, Abdelhafiz AH. The outcome of frailty in older people with diabetes as a function of glycaemic control and hypoglycaemic therapy. Expert Rev Endocrinol Metab 2023; 18(5): 361–375. Dostupné z DOI: <http://dx.doi.org/10.1080/17446651.2023.2239907>.

Kalyani RR, Varadhan R, Weiss CO et al. Frailty Status and Altered Glucose-Insulin Dynamics. J Gerontol A Biol Sci Med Sci 2012; 67(12): 1300–1306. Dostupné z DOI: <http://dx.doi.org/10.1093/gerona/glr141>.

Morley MB, Argiles JM, Evans WJ et al. Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc 2010; 11(6): 391–396. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jamda.2010.04.014>.

Kulkarni AS, Gubbi S, Barzilai N. Benefits of metformin in attenuating the hallmarks of aging. Cell Metab 2020; 32(1): 15–30. Dostupné z DOI: <http://dx.doi.org/10.1016/j.cmet.2020.04.001>.

LeRoith D, Biessels GJ, Braithwaite SS et al. Treatment of diabetes in older adults: An endocrine society* clinical practice guideline. J Clin Endocrinol Metab 2019; 104(5):1520–1574. Dostupné z DOI: <http://dx.doi.org/10.1210/jc.2019–00198>.

Sinclair AJ, Abdelhafiz AH, Forbes A et al. Evidence-based diabetes care for older people with Type 2 diabetes: a critical review. Diabet Med 2019; 36(4): 399–413. Dostupné z DOI: <http://dx.doi.org/10.1111/dme.13859>.

Cheung A, Haas B, Ringer TJ et al. Canadian Study of Health and Aging Clinical Frailty Scale: Does It Predict Adverse Outcomes among Geriatric Trauma Patients? J Am Coll Surg 2017; 225(5): 658–665e. Dostupné z DOI: <https://doi.org/10.1016/j.jamcollsurg.2017.08.008>.

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