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Non-diabetic forms of hypoglycemia in the pediatric population


Authors: Simona Tárnoková 1;  Denisa Lobotková 2;  Katarína Brennerová 2;  Juraj Staní
Authors‘ workplace: Oddelenie laboratórnej medicíny NÚDCH, Bratislava 1;  Detská klinika LF UK a NÚDCH, Bratislava 2;  Laboratórium diabetu a porúch metabolizmu a DIABGENE, Ústav experimentálnej endokrinológie Biomedicínskeho, centra SAV, Bratislava 3
Published in: Forum Diab 2024; 13(3): 125-132
Category: Review Article

Overview

Hypoglycemia is a symptom of a relatively broad group of diseases with different epidemiology, etiology, clinical picture, treatment and prognosis. Children are more susceptible to developing hypoglycemia than adults, as their regulatory processes to maintain stable glycaemia have less capacity. Etiologically, hypoglycemia is a diverse group of diseases, with several being typical of childhood. The most common forms of hypoglycemia in children include insulin treatment in diabetes mellitus, idiopathic ketotic hypoglycemia, hyperinsulinism (in neonatal period), less common but serious causes include deficits of counterregulatory hormones, some inherited metabolic disorders, or intoxication. Their diagnosis is often complex. Determination of ketone bodies is crucial to differentiate the various forms of hypoglycemia. Treatment and prognosis depend mainly on the type of hypoglycemia. This article is dedicated to Non-diabetic hypoglycemias in children.

Keywords:

children – hypoglycemia: aketotic – hypoketotic – ketotic


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