Metabolic syndrome and intestinal microbiome
Authors:
Simona Horná; Juraj Krivuš; Renáta Michalová; Peter Galajda; Marián Mokáň
Authors‘ workplace:
I. interná klinika JLF UK a UNM, Martin
Published in:
Forum Diab 2021; 10(3): 193-196
Category:
Overview
In the last two decades, the intestinal microbiome has become a hot topic in the field of metabolic syndrome, which has reached the dimensions of a pandemic. Research has shown an association between the intestinal microbiome and the metabolic syndrome which is mainly due to the metabolism of short-chain fatty acids, bile acids, impaired intestinal permeability and metabolic endotoxemia. A more accurate understanding of the mechanism of pathogenesis through the intestinal microbiome could lead to improved prevention of a serious health and socio-economic problem, as well as the emergence of new personalized treatment modalities.
Keywords:
obesity – gut microbiome – bile acids – metabolic endotoxemia – short chain fatty acids
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