Pathologia mutans

Czech version

Authors: Petra Kašparová; Ivo Šteiner
Authors‘ workplace: Fingerlandův ústav patologie LFHK a FN, Hradec Králové
Published in: Čes.-slov. Patol., 57, 2021, No. 4, p. 226-231
Category: Original Articles

Overview

The authors present results of our center retrospective study comparing autopsy findings from years 1929 (n=275) and 1989 (n=974). The male to female ratio was very similar in both cohorts (1.3:1 in 1929 and 1.4:1 in 1989). The age range in 1929 was 0-88 years with median of 50 years, whereas in 1989, the age range was 0-98 year and median was 65 years. Among lethal diseases in 1929 were namely infections and infectious complications – 61 % of all patients (out of these, 18 % were tuberculosis cases), neoplasms (12 %) and cardiovascular disorders (6.5 %). In 1989, malignant neoplasms were most frequent (31 %), followed by cardiovascular disorders (21 %) and infections (4.6 % - out of these, tuberculosis represented only 0.6 %).

Our study is unique by comparing two well documented autopsy cohorts in a single center from two years being 60 years apart. The study clearly demonstrates dramatic changes in healthcare achieved during the 20th century.

Keywords:

pathology – healthcare – Autopsy – autopsy findings – lethal diseases

Sources

1. Burton J. A bite into the history of the autopsy (from ancient roots to modern decay). Forensic Science, Medicine, and Pathology 2005; 1(4): 277.

2. Lanjewar DN, Sheth NS, Lanjewar SD, Wagholikar UL. Analysis of causes of death as determined at autopsy in a single institute, the Grant Medical College and Sir J. J. Hospital, Mumbai, India, between 1884 and 1966. Arch Pathol Lab Med 2020; 144: 644-649.

3. Friberg N, Ljungberg O, Berglund D, Ljunberg R, Alafuzoff I, Englund E. Cause of death and significant disease found at autopsy. Virchows Archiv 2019; 475: 781-788.

4. Dehner LP. The medical autopsy: past, present and dubious future. Missouri Medicine 2010; 107(2): 94-100.

5. Panchabhai TS, Patil PD, Shah DR, Joshi AS. An autopsy study of maternal mortality: a tertiary healthcare perspective. J Postgrad Med 2009; 55(1): 8-11.

6. Cox JA, Lukande RL, Lucas S, Nelson AM, Marck E, Colebunders R. Autopsy causes of death in HIV-positive individuals in sub-Saharan Africa and correlation with clinical diagnoses. AIDS Rev 2010; 12(4): 183-194.

7. Juric G, Tentor D, Jakic Razumovic J. Autopsy findings and clinical diagnoses: retrospective study of 3,117 autopsies. Croat Med J 1999; 40(1): 71-76.

8. Wijhe M, McDonald S, Melker HE, Postma M, Wallinga J. Effect of vaccination programmes on mortality burden among children and young adults in the Netherlands during the 20th century: a historical analysis. The Lancet Infectious Diseases 2016; 16(5): 592-598.

9. Cunningham RM, Walton MA, Carter PM. The major causes of death in children and adolescent in the United States. N Engl J Med 2018; 379(25): 2468-2475.

10. Suarez AV, Tsutsui N. The value of museum collections for research and society. BioScience 2004; 54(1).

11. Ryška A, Betlach J. Možnosti využití imunohistochemie pro upřesnění diagnózy z historických parafinových bloků. Cesk Patol 2019; 55(2): 122-125.