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Perinatal outcome of SARS-CoV-2 infection in pregnancy


Authors: Korček Peter 1,2;  Urbancová Hana 3;  Hadravská Šárka 4,5;  Straňák Zbyněk 1,2
Authors‘ workplace: Ústav pro péči o matku a dítě – neonatologie, Praha 1;  3. lékařská fakulta Univerzity Karlovy 2;  Ústav pro péči o matku a dítě – klinická patologie, Praha 3;  Bioptická laboratoř s. r. o., Plzeň 4;  Šiklův ústav patologie, Fakultní nemocnice Plzeň 5
Published in: Čes-slov Pediat 2022; 77 (1): 27-33.
Category: Original Papers

Overview

SARS-CoV-2 placentitis is a rare and serious complication of COVID-19 disease in pregnancy. The coronavirus placental infection may lead to maternal and fetal vascular malperfusion (pregnancy itself is a prothrombotic state), fetal demise, intrauterine hypoxia, fetal growth restriction, or preterm birth with the accompanying neonatal morbidity. In case of transplacental transmission of SARS-CoV-2, newborns can also suffer from early-onset viral pneumonia. Consequently, comprehensive epidemiology control should be implemented during pregnancy (frequent testing, contact tracing, vaccination). Furthermore, anticoagulation prophylaxis (low-molecular-weight heparin) and thorough fetal surveillance may be employed in COVID-positive pregnancies, especially in highrisk cases with preexisting placental insufficiency.

Keywords:

Placenta – SARS-CoV-2 – COVID-19 – perinatology – perinatal morbidity


Sources

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Neonatology Paediatrics General practitioner for children and adolescents
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