#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Cutaneous Amyloidosis. A Review


Authors: E. Sticová 1,2
Authors‘ workplace: Ústav patologie, 3. LF UK a FN Královské Vinohrady, přednosta prof. MUDr. Radoslav Matěj, Ph. D. 1;  Kožní oddělení, Krajská nemocnice Liberec, primář MUDr. Dana Frydrychová 2
Published in: Čes-slov Derm, 98, 2023, No. 1, p. 5-12
Category: Reviews (Continuing Medical Education)

Overview

The term amyloidosis refers to a heterogeneous group of disorders characterized by deposition of misfolded and undegradable proteinaceous material with typical staining properties. Skin is involved in both systemic and localized form of amyloidosis, primary and/or secondary. Amyloid types relevant for cutaneous pathology include amyloid derived from keratin, serum A amyloid, immunoglobulin light chains, β2microglobulin, and transthyretin. The review presents current knowledge about these diseases.

Keywords:

immunohistochemistry – amyloid – AA amyloid – AL amyloid – AK amyloid


Sources

1. AHRAMIYANPOUR, N., AKBARI, Z., SARASYABI, M. S. et al. The therapeutic role of lasers in primary localized cutaneous amyloidosis: a systematic review. Lasers Med Sci., 2022, 37(2), p. 799–813.

2. BLACK, M. M., UPJOHN, E., ALBERT, S. Metabolic and Systemic diseases: Amyloidosis. Bolgonia. In: BOLOGNIA, J. L., JORIZZO, J. L., RAPINI, R. P. et al. Dermatology textbook. 2nd ed., Vol I. Mosby Elsevier, 2008, p. 623–631.

3. DESAI, S. S., RIZZO, M. G., RUSH, A. J., et al. Amyloidoma: a review and case report. Skeletal Radiol., 2021, 50(2), p. 437–444.

4. FERNANDEZ-FLORES, A. Cutaneous amyloidosis: a concept review. Am J Dermatopathol., 2012, 34(1), p. 1–14.

5. GERHARDT, C. A., CARDON, B., RODRIGUEZ-WAITKUS, P. et al. Anosacral amyloidosis in a Chinese-Caribbean male. JAAD Case Rep., 2022, 21, p. 46–48.

6. GUILLET, C., STEINMANN, S., MAUL, JT. et al. Primary Localized Cutaneous Amyloidosis: A Retrospective Study of an Uncommon Skin Disease in the Largest Tertiary Care Center in Switzerland. Dermatology, 2022, 238(3), p. 579-586.

7. HAAS, N., KÜSTER, W., ZUBERBIER, T. et al. Muckle- Wells syndrome: clinical and histological skin findings compatible with cold air urticaria in a large kindred. Br. J. Dermatol., 2004, 151(1), p. 99–104.

8. HAMIE, L., HADDAD, I., NASSER, N. et al. Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis on Atypical Clinical Variants. Am. J. Clin. Dermatol., 2021, 22(5), p. 667–680.

9. HEMMINKI, K., LI, X., FÖRSTI, A. et al. Incidence of hereditary amyloidosis and autoinflammatory diseases in Sweden: endemic and imported diseases. BMC Med. Genet., 2013(14), p. 88.

10. HENDRICKS, C., FERNÁNDEZ FIGUERAS, M. T., LIERSCH, J. et al. Cutaneous Light Chain Deposition Disease: A Report of 2 Cases and Review of the Literature. Am. J. Dermatopathol., 2018, 40(5), p. 337–341.

11. HONSOVA, E., HERMANOVA, M., SVOBODOVA, I. et al. Doporučený postup pro diagnostiku systémových amyloidóz [online]. 2022. Dostupné na www: www.patologie.info/standardy/48.

12. KALTOFT, B., SCHMIDT, G., LAURITZEN, A. F. et al. Primary localised cutaneous amyloidosis – a systematic review. Dan. Med. J., 2013, 60(11), p. A4727.

13. KERL, H. Amyloidosis. In KERL, H. et al. Diagnostic Cutaneous Pathology, © e-Book 2021. Dermatopathology Books, p. 74–86.

14. KRANC, C., WAGNER, R., JOY, N. M. et al. Cutaneous insulin-derived amyloidosis presenting as hyperkeratotic nodules. Cutis, 2021, 107(1), p. E6–E9.

15. LANE, T., LOEFFLER, J. M., ROWCZENIO, D. M. et al. AA amyloidosis complicating the hereditary periodic fever syndromes. Arthritis Rheum., 2013, 65(4), p. 1116–1121.

16. MEHROTRA, K., DEWAN, R., KUMAR, J. V. et al. Primary Cutaneous Amyloidosis: A Clinical, Histopathological and Immunofluorescence Study. J. Clin. Diagn. Res., 2017, 11(8), p. WC01–WC05.

17. PASTERNAK, S., WRIGHT, B. A., WALSH, N. Soft tissue amyloidoma of the extremities: report of a case and review of the literature. Am. J. Dermatopathol., 2007, 29(2), p. 152–155.

18. PATTERSON, J. W. Amyloidosis. In PATTERSON, J. W. et al. Weedon’s Skin Pathology, 5th Ed., © Elsevier 2019, p. 466–473. ISBN: 9780702075827.

19. PICKEN, M. M. Current practice in amyloid detection and typing among renal pathologists. Amyloid, 2011, 18(Suppl 1), p. 73–75.

20. PICKEN, M. M. The Pathology of Amyloidosis in Classification: A Review. Acta Haematol., 2020, 143(4), p. 322–334.

21. SALIM, T., SHENOI, S. D., BALACHANDRAN, C. et al. Lichen amyloidosus: A study of clinical, histopathologic and Immunofluorescence findings in 30 cases. Indian J Dermatol. Venereol. Leprol., 2005, 71, p. 166–169.

22. SAVANT, S. S. Therapeutic regional dermabrasion in papular lichen amyloidosis of shins. Indian J. Dermatol. Venereol. Leprol., 1995, 61(4), p. 196–201.

23. SEKIJIMA, Y. Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease- modifying treatments. J. Neurol. Neurosurg. Psychiatry, 2015, 86(9), p. 1036–1043.

24. SINHA, A., MANJUNATH, G. V., BASAVARAJ, V. Primary cutaneous amyloidosis: A clinicopathological, histochemical, and immunohistochemical study. Indian J. Pathol. Microbiol., 2021, 64(2), p. 323–328.

25. TANAKA, A., ARITA, K., LAI-CHEONG, J. E. et al. New insight into mechanisms of pruritus from molecular studies on familial primary localized cutaneous amyloidosis. Br. J. Dermatol., 2009, 161(6), p. 1217–1224.

26. WALSH, N. M., LANO, I. M., GREEN, P. et al. AL Amyloidoma of the Skin/Subcutis: Cutaneous Amyloidosis, Plasma Cell Dyscrasia or a Manifestation of Primary Cutaneous Marginal Zone Lymphoma? Am. J. Surg. Pathol., 2017, 41(8), p. 1069–1076.

27. WECHALEKAR, A. D., GILLMORE, J. D., HAWKINS, P. N. Systemic amyloidosis. Lancet, 2016, 387(10038), p. 2641–2654.

28. WISNIOWSKI, B., WECHALEKAR, A. Confirming the Diagnosis of Amyloidosis. Acta Haematol., 2020,143(4), p. 312–321.

29. WEIDNER, T., ILLING, T., ELSNER P. Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review. Am. J. Clin. Dermatol., 2017, 18(5), p. 629–642.

30. YAMAN, B., KUMBARACI, B. S., GÓMEZ GONZÁLEZ, C. A. et al. C4d as a Practical Marker for Cutaneous Amyloidosis. Am. J. Dermatopathol., 2022, 44(1), p. 28–32.

31. ZANELLI, M., PALICELLI, A., SANGUEDOLCE, F. et al. Cutaneous Involvement in Diseases with Plasma Cell Differentiation: Diagnostic Approach. Curr Oncol., 2022, 29(5), p. 3026–3043.

32. ZHOU, X., CHEN, Q., TIAN, X. Primary cutaneous amyloidosis of auricular concha. Indian J. Dermatol. Venereol. Leprol., 2020, 86(2), p. 230.

Labels
Dermatology & STDs Paediatric dermatology & STDs
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#