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Generalized Papules and Nodules: Secondary Syphlis. Minireview


Authors: M. Cetkovský 1;  M. Kojanová 1;  M. Důra 1;  O. Kodet 1;  M. Gregová 2;  J. Štork 1
Authors‘ workplace: Dermatovenerologická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. Jiří Štork, CSc. 1;  Ústav patologie 1. LF UK a VFN, Praha, přednosta prof. MUDr. Pavel Dundr, Ph. D. 2
Published in: Čes-slov Derm, 98, 2023, No. 1, p. 26-29
Category:

Overview

The authors describe a case of nodular syphilis with ocular involvement in a 69-year-old immunocompetent heterosexual man. The diagnosis of secondary syphilis was confirmed serologically, histologically and immunohistochemically using T. pallidum antibody. Eye examination confirmed luetic uveitis, examination of cerebrospinal fluid ruled out neurosyphilis. After intravenous 14-day treatment with crystalline penicillin, the skin and eye changes completely healed. The authors present an overview of the current knowledge about this disease.

Keywords:

therapy – imunohistochemistry – nodular syphilis


Sources

1. GLATZ, M., ACHERMANN, Y., KERL, K. et al. Nodular secondary syphilis in a woman. BMJ Case Rep, 2013, 8, p. bcr2013009130.

2. HERNÁNDEZ-BEL, P., LÓPEZ, J., SÁNCHEZ, J. et al. Nodular secondary syphilis. Actas Dermosifiliogr., 2009, 100, p. 520–522.

3. HOOK, E. Syphilis. Lancet, 2017, 389, p. 1550–1557.

4. KUKLOVÁ, I. Syfilis včera a dnes. Dermatol.praxi, 2012, 6, p. 136–137.

5. LITVIK, R. Současná praxe diagnostiky a léčby nejčastějších sexuálně přenosných infekcí. Čes-slov Derm., 2019, 94 (2), p. 47–60.

6. PETTIT, C., MCMURRAY, S., RANDALL, M. B. et al. Highlighting a Potential Pitfall: Positive Treponema pallidum Immunohistochemical Stain in a Patient Without Syphilis. Am J Dermatopathol., 2019, 41(12), p. 924–926.

7. RYSGAARD, C., ALEXANDER, E., SWICK, B. et al. Nodular secondary syphilis with associated granulomatous inflammation: case report and literature rewiew. J Cutan Pathol., 2014, 41, p. 370–379.

8. SANCHEZ, M. R. Syphilis. In WOLFF, K. et al. Fitzpatrick‘ s dermatology in general medicine (7th ed). Vol. 2. New York: McGraw Hill, 2008, p. 1955–1977.

9. SEŇA, A. C., WHITE, B. L., SPARLING, P. F. Novel Treponema pallidum serologic tests: a paradigm shift in syphilis screening for the 21st century. Clin Infect Dis., 2010, 15, 6, p. 700–708.

10. SON, H., PARK, Y., CHUNG, Y. et al. Nodular secondary syphilis in an immunocompetent woman. Dermatologica Sinica, 2018, 36, p. 36–41.

11. TSAI, K. Y., BRENN, T., WERCHNIAK, A. E. Nodular presentation of secondary syphilis. J Am Acad Dermatol, 2007, p. 57–58.

12. WORKOWSKI, K., BACHMANN, L., CHAN, P. et al. Transmitted Infections Treatment Guidelines, 2021. US Department of Health and Human Services/Centers for Disease Control and Prevention, 2021, 70, p. 39–60.

13. www.sukl.cz, SPC Ceftriaxon. Online (dostupné 8.12.2022). Dostupné na www: https://www.sukl.cz/ modules/medication/download.php?file=SPC178606. pdf&type=spc&as=ceftriaxon-kabi-spc.

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