Prenatal diagnosis in estimating the prognosis of sacrococcygeal teratoma
Authors:
Anna Jouzová 1; Lukáš Hruban 1,2; Jakub Turek 3; Martin Jouza 4; Romana Gerychová 1; Tereza Tureková 5; Petr Janků 1,2
Authors‘ workplace:
Gynekologicko-porodnická klinika LF MU a FN Brno
1; Ústav zdravotních věd, LF MU, Brno
2; Klinika dětské chirurgie, ortopedie a traumatologie LF MU a FN Brno
3; Pediatrická klinika LF MU a FN Brno
4; Klinika dětské onkologie LF MU a FN Brno
5
Published in:
Ceska Gynekol 2024; 89(3): 219-223
Category:
doi:
https://doi.org/10.48095/cccg2024219
Overview
: Sacrococcygeal teratoma is a rare congenital malformation, the prognosis depends on factors affecting foetal development. The diagnosis is based on ultrasound examination, especially the evaluation of the detailed morphology of the foetus in the 20th week of pregnancy. Therefore, it is crucial to keep looking for ultrasound markers that would prenatally determine the most accurate prognosis for the foetus. Now, we rely on a small number of studies with a predominance of case reports. We offer a literature review of the essential information concerning sacrococcygeal teratoma diagnostics, therapy, and complications of sacrococcygeal teratomas in connection with prenatal diagnosis. It turns out that in cases with a favourable prognosis according to prenatal ultrasound examination and adequate surgical treatment after childbirth, the prognosis of this congenital malformation is excellent.
Keywords:
sacrococcygeal teratoma – Prognosis – ultrasound – prenatal diagnosis – foetal tumours
Sources
1. Wessell A, Hersh DS, Ho CY et al. Surgical treatment of a type IV cystic sacrococcygeal teratoma with intraspinal extension utilizing a posterior-anterior-posterior approach: a case report. Childs Nerv Syst 2018; 34 (5): 977–982. doi: 10.1007/s00381-018-3718-9.
2. Yoon HM, Byeon S, Hwang JY et al. Sacrococcygeal teratomas in newborns: a comprehensive review for the radiologists. Acta Radiol 2018; 59 (2): 236–246. doi: 10.1177/0284185117710680.
3. Calaminus G, Schneider DT, Bökkerink JP et al. Prognostic value of tumor size, metastases, extension into bone, and increased tumor marker in children with malignant sacrococcygeal germ cell tumors: a prospective evaluation of 71 patients treated in the German cooperative protocols Maligne Keimzelltumoren (MAKEI) 83/86 and MAKEI 89. J Clin Oncol 2003; 21 (5): 781–786. doi: 10.1200/JCO.2003.03.125.
4. Rescorla FJ, Sawin RS, Coran AG et al. Long-term outcome for infants and children with sacrococcygeal teratoma: a report from the childrens cancer group. J Pediatr Surg 1998; 33 (2): 171–176. doi: 10.1016/S0022-3468 (98) 90426-2.
5. Wakhlu A, Misra S, Tandon RK et al. Sacrococcygeal teratoma. Pediatr Surg Int 2002; 18 (5–6): 384–387. doi: 10.1007/s00383-002-0729-z.
6. Kops AL, Hulsker CC, Fiocco M et al. Malignant recurrence after mature Sacrococcygeal teratoma: a meta-analysis and review of the literature. Crit Re Oncol Hematol 2020; 156: 103140. doi: 10.1016/j.critrevonc.2020.103140.
7. Wang Y, Wu Y, Wang L et al. Analysis of recurrent sacrococcygeal teratoma in children: clinical features, relapse risks, and anorectal functional sequelae. Med Sci Monit 2017; 23: 17–23. doi: 10.12659/MSM.900400.
8. Krishan S, Solanki R, Sethi S. Sacrococcygeal teratoma – role of ultrasound in antenatal diagnosis and management. J HK Coll Radiol 2004; 7: 35–39.
9. Stefanovic V, Halmesmäki E. Peripartum ultrasound-guided drainage of cystic fetal sacrococcygeal teratoma for the prevention of the labor dystocia: a report of two cases. Am J Perinatol Rep 2011; 1 (2): 87–90. doi: 10.1055/s-0031-1284220.
10. Danzer E, Hubbard AM, Hedrick HL et al. Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MRI. Am J Roentgenol 2006; 187 (4): W350–W356. doi: 10.2214/AJR.05.0152.
11. Sinha S, Sarin YK, Deshpande VP. Neonatal sacrococcygeal teratoma: our experience with 10 cases. J Neonatal Surg 2013; 2 (1): 4.
12. Van Mieghem T, Al-Ibrahim A, Deprest J et al. Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. Ultrasound Obstet Gynecol 2014; 43 (6): 611–619. doi: 10.1002/uog.13315.
13. Seilern und Aspang J, Burnand KM, Ong HL et al. Sacrococcygeal teratoma with intraspinal extension: a case series and review of literature. J Pediatr Surg 2020; 55 (10): 2022–2025. doi: 10.1016/j.jpedsurg.2020.02.003.
14. Sun DJ, Lee JN, Long CY et al. Early diagnosis of fetal sacrococcygeal teratoma: a case report. Kaohsiung J Med Sci 2003; 19 (6): 313–315. doi: 10.1016/S1607-551X (09) 70478-4.
15. Avni FE, Guibaud L, Robert Y et al. MR imaging of fetal sacrococcygeal teratoma: diagnosis and assessment. Am J Roentgenol 2002; 178 (1): 179–183. doi: 10.2214/ajr.178.1.1780179.
16. Moreira Rios LT, Araujo Júnior E, Machado Nardozza LM et al. Prenatal diagnosis of sacrococcygeal teratoma using two and three-dimensional ultrasonography. Case Rep Obstet Gynecol 2012; 2012: 131369. doi: 10.1155/2012/ 131369.
17. Antunes E, Werner H Jr, Daltro PA et al. Correlação entre os achados ultra-sonográficos e de ressonância magnética no teratoma sacrococcígeo fetal. Radiol Bras 2008; 41 (3): 163–166. doi: 10.1590/S0100-39842008000300007.
18. Moradi B, Sadrarhami S, Banihashemian M et al. Ultrasonography and magnetic resonance imaging in a fetus with sacrococcygeal teratoma: a case report. J Obstet Gynecol Cancer Res 2018; 3 (4): 165–168. doi: 10.30699/jogcr.3.4.26.
19. Firszt OP, Myga-Porosiło J, Pośpieszny K et al. Radiological features of sacrococcygeal teratomas in fetal magnetic resonance imaging and computed tomography – a case report. Pol J Radiol 2018; 83: e19–e23. doi: 10.5114/pjr.2018.74861.
20. Yadav DK, Acharya SK, Bagga D et al. Sacrococcygeal teratoma: clinical characteristics, management, and long-term outcomes in a prospective study from a tertiary care center. J Indian Assoc Pediatr Surg 2020; 25 (1): 15–21. doi: 10.4103/jiaps.JIAPS_219_18.
21. Cal M, de Carvalho RM, Clode N. Prenatal diagnosis of sacrococcygeal teratoma. Medicine 2016; 10: 340–341.
22. Ho KO, Soundappan SV, Walker K et al. Sacrococcygeal teratoma: the 13‐year experience of a tertiary paediatric centre. J Paediatrics Child Health 2011; 47 (5): 287–291. doi: 10.1111/j.1440-1754.2010.01957.x.
23. Rattan KN, Singh J. Neonatal sacrococcygeal teratoma: our 20-year experience from a tertiary care centre in North India. Trop Doct 2021; 51 (2): 209–212. doi: 10.1177/0049475520973616.
24. Partridge EA, Canning D, Long C et al. Urologic and anorectal complications of sacrococcygeal teratomas: prenatal and postnatal predictors. J Pediatr Surg 2014; 49 (1): 139–143. doi: 10.1016/j.jpedsurg.2013.09.042.
25. Villamil V, Girón Vallejo O, Fernández-Ibieta M et al. Functional and aesthetic evaluation of sacrococcygeal teratomas. Not everything ends with surgery. An Pediatr (Engl Ed) 2018; 88 (1): 39–46. doi: 10.1016/j.anpede.2017.03.013.
26. van Heurn LJ, Coumans AB, Derikx JP et al. Factors associated with poor outcome in fetuses prenatally diagnosed with sacrococcygeal teratoma. Prenat Diagn 2021; 41 (11): 1430–1438. doi: 10.1002/pd.6026.
27. Le LD, Alam S, Lim FY et al. Prenatal and postnatal urologic complications of sacrococcygeal teratomas. J Pediatr Surg 2011; 46 (6): 1186–1190. doi: 10.1016/j.jpedsurg.2011.03.045.
28. Hirose S, Farmer DL. Fetal surgery for sacrococcygeal teratoma. Clin Perinatol 2003; 30 (3): 493–506. doi: 10.1016/S0095-5108 (03) 00059-9.
29. Dedushi K, Kabashi S, Mucaj S et al. Magnetic resonance imaging verification of a case of sacrococcygeal teratoma. World J Oncol 2016; 7 (4): 81–84. doi: 10.14740/wjon965w.
30. Neubert S, Trautmann K, Tanner B et al. Sonographic prognostic factors in prenatal diag- nosis of SCT. Fetal Diagn Ther 2004; 19 (4): 319–326. doi: 10.1159/000077959.
31. Schwab M (ed). Encyclopedia of cancer. Berlin: Springer Berlin Heidelberg 2011. doi: 10.1007/978-3-642-16483-5.
32. Derikx JP, de Backer A, van de Schoot L et al. Factors associated with recurrence and metastasis in sacrococcygeal teratoma. Br J Surg 2006; 93 (12): 1543–1548. doi: 10.1002/bjs.5379.
33. Schmidt K, Silverman N, Harison M et al. High-output cardiac failure in fetuses with large sacrococcygeal teratoma: diagnosis by echocardiography and Doppler ultrasound. J Pediatr 1989; 114 (6): 1023–1028. doi: 10.1016/s0022-3476 (89) 80456-1.
34. Wohlmuth C, Bergh E, Bell C et al. Clinical monitoring of sacrococcygeal teratoma. Fetal Diagn Ther 2019; 46 (5): 333–340. doi: 10.1159/000496841.
35. Gucciardo L, Uyttebroek A, De Wever I et al. Prenatal assessment and management of sacrococcygeal teratoma. Prenat Diagn 2011; 31 (7): 678–688. doi: 10.1002/pd.2781.
36. Hirose S, Sydorak RM, Tsao K et al. Spectrum of intrapartum management strategies for giant fetal cervical teratoma. J Pediatr Surg 2003; 38 (3): 446–450. doi: 10.1053/jpsu.2003.50077.
37. Gebb JS, Khalek N, Qamar H et al. High tumor volume to fetal weight ratio is associated with worse fetal outcomes and increased maternal risk in fetuses with sacrococcygeal teratoma. Fetal Diagn Ther 2019; 45 (2): 94–101. doi: 10.1159/000486782.
38. Shue E, Bolouri M, Jelin EB et al. Tumor metrics and morphology predict poor prognosis in prenatally diagnosed sacrococcygeal teratoma: a 25-year experience at a single institution. J Pediatr Surg 2013; 48 (6): 1225–1231. doi: 10.1016/j.jpedsurg.2013.03.016.
39. Tuladhar R, Patole SK, Whitehall JS. Sacrococcygeal teratoma in the perinatal period. Postgrad Med J 2000; 76 (902): 754–759. doi: 10.1136/pgmj.76.902.754.
40. Kremer ME, Althof JF, Derikx JP et al. The incidence of associated abnormalities in patients with sacrococcygeal teratoma. J Pediatr Surg 2018; 53 (10): 1918–1922. doi: 10.1016/j.jpedsurg.2018. 01.013.
41. Halleran DR, Vilanova-Sanchez A, Reck CA et al. Presacral masses and sacrococcygeal teratomas in patients with and without anorectal malformations: a single institution comparative study. J Pediatr Surg 2019; 54 (7): 1372137–8. doi: 10.1016/j.jpedsurg.2018.11.009.
42. Litwińska M, Litwińska E, Janiak K et al. Percutaneous intratumor laser ablation for fetal sacrococcygeal teratoma. Fetal Diagn Ther 2020; 47 (2): 138–144. doi: 10.1159/000500775.
43. Litwińska M, Litwińska E, Janiak K et al. Percutaneous intratumor laser ablation for fetal sacrococcygeal Teratoma. Fetal Diagn Ther 2020; 47 (2): 137–144. doi: 10.1159/000500775.
44. Barakat MI, Abdelaal SM, Saleh AM. Sacrococcygeal teratoma in infants and children. Acta Neurochir 2011; 153 (9): 1781–1786. doi: 10.1007/s00701-011-1048-8.
45. Bhuta R, Shah R, Gell JJ et al. Children’s oncology group’s 2023 blueprint for research: germ cell tumors. Pediatr Blood Cancer 2023; 70 (Suppl 6): e30562. doi: 10.1002/pbc.30562.
46. Ramadani HM. The management of prenatally diagnosed sacrococcygeal teratoma. Ann Saudi Med 1992; 12 (5): 484–488. doi: 10.5144/0256- 4947.1992.484.
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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
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