Reccurent pregnancy loss – review

Czech version

Authors: R. Jarošová ^1,2; J. Mašata ¹; D. Stejskal ²; M. Brandejská ²
Published in: Ceska Gynekol 2013; 78(2): 200-205

Overview

Objective:
Informative review of possible causes and therapy of habitual pregnancy loss and infertility.

Design:
Review.

Settings:
Department of Gynecology and Obstetrics, General Faculty Hospital of Charles University, Prague.

Subject and method:
The repeated (habitual) loss of pregnancy is defined by three or more spontaneous abortions. Approximately 0,4 to 1% of women are affected. The pregnancy loss is more frequent in women younger than 20 and older than 35 years. The frequency of spontaneous abortions parallels the number of previous pregnancies. The causative treatment of women with recurring abortions is not available, however, it is recommended that such women are evaluated by available methods to eliminate etiological causes of repeated pregnancy losses.

Conlusions:
Effective therapy is possible when the diagnostic reason for repeated abortions is determined. Nevertheless, the causes leading to repeated pregnancy losses are identified only in approximately 12% of women. However, alleged and unexplained infertility, resulting in habitual pregnancy losses has a favorable prognosis.

Keywords:
reccurent pregnancy loss – age of the mother – genetic factors – antiphospholipid syndrome – inherited trombophilia – endometriosis

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