Importance of Clinical Prognostic Factors in OvarianCancer

Czech version

Authors: J. Špaček ¹; J. Petera ²; Z. Tesařík ³
Authors‘ workplace: Klinika porodnictví a gynekologie, UK, LF v Hradci Králové, přednosta doc. MUDr. J. Tošner, CSc. 2Klinika onkologie a radioterapie, UK, LF v Hradci Králové, přednosta doc. MUDr. J. Petera, PhD. 3Bristol-Myers Squibb, s. r. o., Onkologická divize, Praha ¹
Published in: Ceska Gynekol 2002; (5): 280-285
Category:

Overview

Objective:
To present a review of clinical prognostic factors in ovarian cancer.Subject: Review.Setting: Department of Obstetrics and Gynaecology, Medical Faculty Hradec Králové, CharlesUniversity, Prague; Department of Clinical Oncology, Medical Faculty Hradec Králové, CharlesUniversity, Prague; Bristol-Myers Squibb, Department of Oncology, Prague.Subject and Method: Discussion about current evidence from literature.Conclusion: Epithelial ovarian cancers are characterized by a broad spectrum of biological behaviorranging from tumors that have an excellent prognosis and high likelihood of cure to thosethat progress rapidly and have a very poor prognosis. This wide clinical spectrum is partly reflectedby a number of clinical prognostic variables. The most important of these clinical factors isstage, volume of residual tumor remaining after surgical resection, performance status and age,interval between end of primary therapy and beginning of recurrence, drug resistance.

Key words:
ovarian cancer, clinical prognostic factor, stage, tumor residuum, drug resistance

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