Bacteriocins produced by lactic acid bacteria
Authors:
Andrea Bilková; Hana Kiňová Sepová; František Bilka; Andrea Balážová
Authors‘ workplace:
Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra bunkovej a molekulárnej biológie liečiv
Published in:
Čes. slov. Farm., 2011; 60, 65-72
Category:
Review Articles
Overview
Lactic acid bacteria comprise several genera of gram–positive bacteria that are known for the production of structurally different antimicrobial substances. Among them, bacteriocins are nowadays in the centre of scientific interest. Bacteriocins, proteinaceous antimicrobial substances, are produced ribosomally and have usually a narrow spectrum of bacterial growth inhibition. According to their structure and the target of their activity, they are divided into four classes, although there are some suggestions for a renewed classification. The most interesting and usable class are lantibiotics. They comprise the most widely commercially used and well examined bacteriocin, nisin. The non-pathogenic character of lactic acid bacteria is advantageous for using their bacteriocins in food preservation as well as in feed supplements or in veterinary medicine.
Key words:
lactic acid bacteria – probiotics – bacteriocins – lantibiotics – nisin – biopreservation
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Czech and Slovak Pharmacy
2011 Issue 2
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