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New diagnostic criteria of multiple myeloma


Authors: V. Maisnar
Authors‘ workplace: IV. interní hematologická klinika, FN a LF UK Hradec Králové
Published in: Klin. Biochem. Metab., 24, 2016, No. 3, p. 127-128

Overview

The new diagnostic criteria was published by the International myeloma working group at the end of 2014 already. Particularly changes in multiple myeloma (MM) and its “smoldering” form are so fundamental that we could not wait with their publication to the next release of overall recommendations. Therefore Czech Myeloma Group responded by issuing Supplement no. 2 of its guidelines. The aim of this article is to introduce the newly recommended criteria for the diagnosis of MM, including a comparison with the previous criteria.

Key words:
multiple myeloma, criteria of diagnosis, new recommendations.


Sources

1. Hájek, R., Adam, Z., Ščudla, V. et al. Souhrn doporučení 2012. Diagnostika a léčba mnohočetného myelomu. Transfuze Hematol dnes 2012, 18 (Suppl 1): p. 1-89.

2. Rajkumar, S. V., Dimopoulos, M. A., Palumbo, A. et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol 2014, 15: e538-48.

3. Mateos, M. V., Hernández, M. T., Giraldo, P. et al. Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma. N Engl. J. Med., 2013, 369: 438-47.

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