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Heart rate and cardiovascular risk: What does the BEAUTIFUL study say?


Authors: F. Kölbel
Published in: Kardiol Rev Int Med 2008, 10(4): 159-163

Overview

The BEAUTIFUL study has shown that even tho ugh mostly combined with beta blockers, ivabradine has reduced, in a statistically significant way, the need for hospitalisati on and for coronary revascularisati on due to fatal and non‑fatal infarcti on in IHD pati ents with impaired left ventricular functi on and ≥ 70 be ats/ min baseline he art rate. It has also proven that he art rate is a significant prognostic sign in the monitored populati on of pati ents which deserves systematic attenti on. Another important finding is the fact that ivabradine as a drug the effect of which is bo und to the capacity to reduce he art rate can be safely combined with beta blockers which still form part of the basic medicati on for IHD pati ents.

Key words:
ivabradine – heart rate – beta blockers


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Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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