Myocardial infarction in elderly pacients
Authors:
O. Dostál; prof. MUDr. Jan Bělohlávek, Ph.D.; T. Kovárník; P. Kuchynka; A. Linhart
Authors‘ workplace:
1. LF UK a VFN, Praha
; II. interní klinika kardiologie a angiologie
Published in:
Kardiol Rev Int Med 2007, 9(2): 82-88
Category:
Editorial
Overview
Acute myocardial infarction is serious life-threatening illness. In elderly patients, their biological age, besides heart failure in the initial phase of hospitalization is considered to be one of most significant negative prognostic markers. Authors discuss differences in older and younger population of patients suffering acute myocardial infarction in regards both to risk factors and therapeutic approach and present their own experience.
Key words:
acute myocardial infarction, elderly patients, coronary care unit, heart failure
Sources
1.Widimský P, Špaček R. Infarkt myokardu – úvodní poznámky. In: Aschermann M et al (eds). Kardiologie. Praha: Galén 2004: vol. 1, 688-689.
2.Dušek J et al. Pokles celkové a sezónní úmrtnosti pro infarkt myokardu v České republice v letech 1994-2003. Cor Vasa 2006; 48(4): 21.
3.ÚZIS – ČR, Aktuální informace č. 13/2004.
4.ÚZIS – ČR, Informace ze zdravotnictví Moravskolslezského kraje č. 20/2003.
5.ÚZIS – ČR, Informace ze zdravotnictví Královéhradeckého kraje č. 02/2002.
6.Burke AP, Kolodgie FD et al. Healed plaque ruptures and sudden coronary death, evidence that subclinical rupture has a role in plaque progression. Circulation 2001; 103: 934-940.
7.Gotwalles Y et al. Acute STEMI in old pateints. The real life. Ann Cardiol Angeiol 2004; 53(6): 305-313.
8.Helmy T, Patel AD, Wenger NK et al. Evidence-based management of coronary artery disease in the elderly – current prospectives. Med Gen Med 2005; 7(2): 75.
9.Internetová dokumentace - www.eamos.cz
10.LaCroix AZ, Guralnik JM, Curb JD et al. Chest pain and coronary heart disease mortality among older men and women in three communites. Circulation 1990; 81: 437-446.
11.Dangelser G et al. Acute ST – elevation myocardial infarction in the elderly (> 75 years). Results from a regional multicenter study. Presse Med 2005; 34(14): 983-989.
12.Wehrens XH, Doevendans PA. Cardiac rupture complicating myocardial infarction. Int J Cardiol 2004; 95(2-3): 285-292.
13.Joussein-Remacle S, Delarche N, Bader H et al. Risk factors in young population with acute myocardial infarction: one year prospective study. Ann Cardiol Angeiol 2006; 55(4): 204-209.
14.Miyamoto S, Goto Y, Sumida H, Yasuda et al. Risk factors and physicial aktivity levels at the onset of acute myocardial infarction in young men. J Cardiol 2000; 36(2): 75-83.
15.Internetová dokumentace – www.tasc-pad.org
16.Hertzer NR, Beven EG, Young JR et al. Coronary artery disease in peripheral vascural patients: a classification of 1000 coronary angiograms and results of surgical management. Ann Surg 1984; 199: 223-233.
17.Kronmal RA, Barzilay JI, Smith NL et al. Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001. PLoS Med 2006; 3(10): 400.
18.Newman AB, Siscovick DS, Manolio TA. Ankle-arm index as a marker of atherosclesrosis in the Cardiovascular Health Study. Circulation 1993; 88: 837-845.
19.Hennerici M, Aulich A, Sandeman W. Incidence of asymptomatic extracranial arterial disease. Stroke 1981; 12: 750-758.
20.Widimský P, Janoušek S, Vojáček J. Doporučení pro diagnostiku a léčbu akutního infarktu myokardu, (Q typ/ s elevacemi ST/ s raménkovým blokem). guidelines České kardiologické společnosti č. 24, internetová dokumentace – www.kardio.cz, resp. Cor Vasa 2002; 44(7/8): K123-K143.
21.De Gevigney G, Delahaye F, Staat P. Heart failure and myocardial infarction in the elderly. For its more specific management. Presse Med 2003; 32(22): 1033-1038.
22.Wilbert S, Aronow WS. Treatment of unstable Angina Pectoris/Non-ST-segment elevation myocardial infarction in elderly patiens. J Gerontol A Bio Sci Med Sci 2003; 58(10): 927-933.
23.Mangoni AA, Jackson SH. The implication of growing evidence base for drug use in elderly patients. Part 3. – beta adrenoreceptor blockers in heart failure and thrombolytics in acute myocardial infarction. Br J Clin Pharmacol 2006; 61(5): 521-528.
24.Levy P, Lechat P, Leizovicz A et al. A cost minimalization of heart failure therapy with bisoprolol in the French settings an analysis from CIBIS trial data. Cardiac Insufficiency Bisoprolol Study. Cardiovasc Drug Ther 1998; 12(3): 301-305.
25.Domanski MJ, Krause-Steinrauf H, Massie BM et al. A komparativ analysis from 4 trials of beta – blocker therapy for heart failure: BEST, CIBIS II, MERIT-HF and COPERNICUS. J Card Fail 2003; 9(5): 354-363.
26.Mc Queen MJ, Lonn E, Gerstain HC et al. The HOPE (Heart Outcomes Prevention Evaluation) Study and its consequences. Scand J Clin Lab Incest Suppl 2005; 240: 143-156.
27.Ceconi C, Fox KM, Remme WJ et al. ACE inhibition with perindopril and endothelial function. Results of a substudy of the EUROPA study: PERTINENT. Cardiovasc Res 2007; 73(1): 237-246.
28.Sica DA. New considerations relating to vlase effect with angiotenzin-converting enzyme inhibitors – the PEACE study. J Clin Hypertens 2005; 7(3): 188-193.
29.Pitt B. Effect of aldosteron blockade in patiens with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies. Mol Cell Endocrionol 2004; 217(1-2): 53-58.
30.White HD, Aylward PE, Huong Z et al. Mortality and morbidity Romain high despote captopril and/or Valsartan therapy in elderly patints with left ventricular systolic dysfunction, heart failure or both after acute myocardial infarction: results from the Valsartan in Acute Myocardial Infarction Trial (VALIANT). Circulation 2005; 112(22): 3391-3399.
31.Pfeffer MA, McMurray JJ, Velaquez EJ et al. Vlasartan, cpatopril or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003; 349: 1893-1906.
32.Haffner SM, Alexandr CM, Cook TJ et al. Reduced coronary events in simvastatin-treated patiens with coronary heart disease and diabetes or impaired fasting glukose levels: subgroup analyse in the Scandinavian Simvastatin Survival Study. Arch Intern Med 1999; 159: 2661-2667.
33.Philippe F. Value and role of lipid lowering therapy for cardiovascular prevention in the elderly. Ann Cardiol Angeiol 2003; 52(4): 246-253.
34.Ray KK, Canon CP. Intensive statin therapy in acute coronary syndromes: clinical benefits and vascular biology. Curr Opin Lipidol 2004; 15(6): 637-643.
35.Evans M, Roberts A Dares S et al. Medical lipid regulating therapy: current evidence, ongoing trials and future developments. Drugs 2004; 64(11): 1181-1196.
36.Mehta RH, Havaji KJ, Cox D et al. Clinical and angiographic correlates and outcomes of suboptimal coronary flow in patiens with acute myocardial infarction undergoing primary percutaneous coronary intervention. J Am Coll Cardiol 2003; 42(10): 1739-1746.
37.Mehta AB, Abhyankar AD. Sion thrombolysis trial – randomised trial of intravenous thrombolysis and primary percutaneus transluminal coronary angiography for acute myocardial infarction (AMI) – feasibility phase data of angioplaty limb. J Assoc Physicians India 1994; 42(1): 43-44.
38.Fintel DJ, Ledley GS. Management of patiens with non ST-segment elevation acute coronary syndroms: insight from the PURSUIT trial. Clin Cardiol 2000; 23(Suppl 5): 1-12.
39.Tetros SJ, Snapin SM, Wan Y et al. Tirofiban therapy for patiens with acute coronary syndromes and prior coronary vypase grafting in the PRISM-PLUS trial. Am J Cardiol 2004; 93(7): 843-847.
40.Chan AW, Moliterno DJ. Defining the role of abciximab for acute coronary syndromes: lessons from CADILLAC, ADMIRAL, GUSTO IV, GUSTO V and TARGET trials. Curr Opin Cardiol 2001; 16(6): 375-383.
41.Mc Kay RG, Boden WE. Small peptide GP IIb/III receptor inhibitors as upstream therapy in non ST-segment elevation acute coronary syndromes: results of the PURSUIT, PRISM, PRISM-PLUS, TACTICS and PARAGON trials. Curr Opin Cardiol 2001; 16(6): 364-369.
42.Benner JS et al. Long-term perzistance in use of statin therapy in elderly patiens. JAMA 2002; 288: 455-461.
43.Hochman JS, Sleeper LA, Webb JG et al. Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK investigators. N Engl J Med 1999; 341: 625-634.
44.Critchley JA, Capewell S. Mortality risk reduction associated with smoking cessation in patinets with coronary hearth disease: a systemic review. JAMA 2003; 290: 86-97.
45.Hanna IR, Wenger NK. Secondary prevention of coronary hearth disease in elderly patiens. Am Fam Physician 2005; 71(12): 2289-2296.
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Paediatric cardiology Internal medicine Cardiac surgery CardiologyArticle was published in
Cardiology Review
2007 Issue 2
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