VV‑ECMO in organ donor after brain death – case report and review of the issue

Czech version

Authors: B. Stadlerová ^1,2*; R. Černá Pařízková ^4*; J. Škola ^1,2; R. Škulec ^1,3,4; E. Pokorná ⁵; P. Šustek ⁶; L. Prudil ⁷; V. Černý ^{1,4,8,9,10,11}
Authors‘ workplace: Autoři měli na přípravě článku stejný podíl a jsou označeni jako prvoautoři. ^*; Klinika anesteziologie, perioperační a intenzivní medicíny Fakulty zdravotnických studií Univerzity J. E. Purkyně v Ústí nad Labem a Krajské zdravotní, a. s. – Masarykovy nemocnice v Ústí nad Labem, o. z. ¹; Univerzita Karlova, Lékařská fakulta v Hradci Králové ²; Zdravotnická záchranná služba Středočeského kraje, Kladno ³; Klinika anesteziologie, resuscitace a intenzivní medicíny, Univerzita Karlova, Lékařská fakulta v Hradci Králové, Fakultní nemocnice Hradec Králové ⁴; Odborné edukační pracoviště pro dárcovství orgánů, Institut klinické a experimentální medicíny, Praha 4 ⁵; Centrum zdravotnického práva a Katedra občanského práva, Právnická fakulta Univerzity Karlovy, Praha ⁶; AK Prudil a spol., s. r. o., Brno ⁷; Centrum pro výzkum a vývoj, Fakultní nemocnice Hradec Králové ⁸; Institut postgraduálního vzdělávání ve zdravotnictví v Praze ⁹; Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada ¹⁰; Technická univerzita v Liberci ¹¹
Published in: Anest. intenziv. Med., 33, 2022, č. 3-4, s. 164-169
Category: Case Report
doi: https://doi.org/10.36290/aim.2022.026

Overview

The lack of suitable organs is a global problem for transplant medicine. Donors with brain death represent the most common group of organ donors in developed countries and the Czech Republic. After brain death, organ dysfunction often develops, which can lead to organ damage and affect its viability for successful transplantation. Extracorporeal membrane oxygenation is an effective option of circulatory and lung support in the event of failure of normal procedures. The case report describes the clinical course of a 36-year-old donor with proven brain death who was connected to venous ECMO to bridge severe hypoxemia as a bridging technique for organ donation. The article discusses professional, legal and ethical issues with the definition of possibilities and conditions under which this procedure can be used.

Keywords:

organ donation – ECMO – DBD

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