Guidelines for the treatment of invasive aspergillosis

Czech version

Authors: Ráčil Zdenek ¹; Mayer Jiří ¹; Kocmanová Iva ²; Haber Jan ³; Mallátová Naďa ⁴; Kouba Michal ⁵; Sedláček Petr ⁶; Faber Edgar ⁷; Herold Ivan ⁸; Múdry Peter ⁹; Drgoňa Luboš ¹⁰; Karas Michal ¹¹; Buchta Vladimír ¹²; Vydra Jan ¹³; Kolář Michal ¹⁴; Trupl Jan ¹⁵; Marešová Vilma ¹⁶; Rozsypal Hanuš ¹⁶; Nyč Otakar ¹⁷; Cwiertka Karel ¹⁸
Authors‘ workplace: Interní hematoonkologická klinika, FN Brno ¹; Oddělení klinické mikrobiologie, FN Brno ²; I. interní klinika – hematoonkologická VFN, Praha ³; Laboratoř lékařské parazitologie a mykologie, Centrální laboratoře, Nemocnice České Budějovice, a. s. ⁴; Ústav hematologie a krevní transfuze Praha ⁵; Klinika dětské hematologie a onkologie FN Motol, Praha ⁶; Hematoonkologická klinika FN Olomouc ⁷; ARO, Klaudiánova nemocnice Mladá Boleslav ⁸; Klinika dětské onkologie, FN Brno ⁹; Národný onkologický ústav, Bratislava, Slovensko ¹⁰; Hematologicko-onkologické oddělení FN Plzeň ¹¹; Ústav klinické mikrobiologie FN Hradec Králové ¹²; Oddělení klinické hematologie FNKV Praha ¹³; KAR VFN, Praha ¹⁴; Klinika laboratorní medicíny SYNLAB, s. r. o., Bratislava, Slovensko ¹⁵; Infekční klinika FN Na Bulovce, Praha ¹⁶; Ústav lékařské mikrobiologie FN Motol, Praha ¹⁷; Onkologická klinika FN Olomouc ¹⁸
Published in: Anest. intenziv. Med., 20, 2009, č. 1, s. 48-56
Category: The recommendations of professional societies

Overview

An increasing incidence of invasive aspergillosis is observed in most immunocompromised patients, and especially in patients with acute leukemia and following haematopoietic stem cell transplantation. In order to decrease mortality due to this infection, clinicians need to optimize their treatment choices.

The objective of these guidelines is to summarize the current evidence for the treatment of invasive aspergillosis. The recommendations have been developed by an expert panel following an evidence-based literature search with regard to current recommendations of the European Conference in Infections in Leukemia and Infectious Diseases Society of America.

Key words:
invasive aspergillosis – treatment guidelines – antimycotics

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Article was published in

Anaesthesiology and Intensive Care Medicine

2009 Issue 1