PLOS Genetics - Číslo 6/2015

Perspective

32767

Orphan Genes Find a Home: Interspecific Competition and Gene Network Evolution

Minor Cause—Major Effect: A Novel Mode of Control of Bistable Gene Expression

Connecting Circadian Genes to Neurodegenerative Pathways in Fruit Flies

Expression of Concern

32767

Expression of Concern: RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells

Formal Comment

32767

Response to “Ribosome Rescue and Translation Termination at Non-standard Stop Codons by ICT1 in Mammalian Mitochondria”

Response to the Formal Letter of Z. Chrzanowska-Lightowlers and R. N. Lightowlers Regarding Our Article “Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria”

Research Article

32767

Germline Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia

Leveraging Identity-by-Descent for Accurate Genotype Inference in Family Sequencing Data

Is Required for the Expression of Principal Recognition Molecules That Control Axon Targeting in the Retina

Epigenetic Aging Signatures Are Coherently Modified in Cancer

Silencing of DNase Colicin E8 Gene Expression by a Complex Nucleoprotein Assembly Ensures Timely Colicin Induction

A Transposable Element within the Non-canonical Telomerase RNA of Modulates Telomerase in Response to DNA Damage

The Orphan Gene Regulates Dauer Development and Intraspecific Competition in Nematodes by Copy Number Variation

9--13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease

Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination

The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding

MreB-Dependent Inhibition of Cell Elongation during the Escape from Competence in

DNA Damage Regulates Translation through β-TRCP Targeting of CReP

Multiple In Vivo Biological Processes Are Mediated by Functionally Redundant Activities of and

The Analysis of () Mutants Reveals Differences in the Fusigenic Potential among Telomeres

The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in .

Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

The . Accessory Helicase PcrA Facilitates DNA Replication through Transcription Units

AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance

Npvf: Hypothalamic Biomarker of Ambient Temperature Independent of Nutritional Status

Transfer RNAs Mediate the Rapid Adaptation of to Oxidative Stress

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

Non-reciprocal Interspecies Hybridization Barriers in the Capsella Genus Are Established in the Endosperm

Canine Spontaneous Head and Neck Squamous Cell Carcinomas Represent Their Human Counterparts at the Molecular Level

Genetic Changes to a Transcriptional Silencer Element Confers Phenotypic Diversity within and between Species

Functional Assessment of Disease-Associated Regulatory Variants Using a Versatile Dual Colour Transgenesis Strategy in Zebrafish

Translational Upregulation of an Individual p21 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

Independent Neuronal Origin of Seizures and Behavioral Comorbidities in an Animal Model of a Severe Childhood Genetic Epileptic Encephalopathy

The Human Blood Metabolome-Transcriptome Interface

A Common Cancer Risk-Associated Allele in the Locus Encodes a Dominant Negative Inhibitor of Telomerase

A Legume Genetic Framework Controls Infection of Nodules by Symbiotic and Endophytic Bacteria

The Eukaryotic-Like Ser/Thr Kinase PrkC Regulates the Essential WalRK Two-Component System in

The Yeast GSK-3 Homologue Mck1 Is a Key Controller of Quiescence Entry and Chronological Lifespan

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

Exome Sequencing of Phenotypic Extremes Identifies and as Interacting Modifiers of Chronic Infection in Cystic Fibrosis

The Role of -Mediated Epigenetic Silencing in the Population Dynamics of Transposable Elements in

Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in

Abnormal Activation of BMP Signaling Causes Myopathy in Null Mice

Reproductive Mode and the Evolution of Genome Size and Structure in Nematodes

Replication and Active Partition of Integrative and Conjugative Elements (ICEs) of the SXT/R391 Family: The Line between ICEs and Conjugative Plasmids Is Getting Thinner

Motor and Sensory Deficits in the Mice Result from Mutation of the ESCRT Component HGS

Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

Lipophorin Receptors Recruit the Lipoprotein LTP to the Plasma Membrane to Mediate Lipid Uptake

Separable Crossover-Promoting and Crossover-Constraining Aspects of Zip1 Activity during Budding Yeast Meiosis

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4

Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth

Necrotic Cells Actively Attract Phagocytes through the Collaborative Action of Two Distinct PS-Exposure Mechanisms

A Novel Feedback Loop That Controls Bimodal Expression of Genetic Competence

PLOS Genetics

2015 Číslo 6

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