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Brodalumab – 5 Years of Data on Efficacy, Safety, and Quality of Life Improvement in Plaque Psoriasis
20. 4. 2020 Source: Topical Treatment of PsoriasisChronic inflammatory diseases, including psoriasis, require therapeutic approaches that maintain efficacy and tolerability even during long-term treatment. One such modern modality is brodalumab, a fully human monoclonal antibody against the A subunit of the interleukin (IL) 17 receptor. A study published last year evaluated its long-term efficacy and safety in patients with moderate to severe plaque psoriasis and also focused on improving their quality of life.
Impact of Candesartan on Achieving Remission in Patients with Active IgA Nephropathy
IgA nephropathy is the most common glomerulonephritis worldwide and in the Czech Republic. The effect of candesartan (an angiotensin receptor blocker) on the remission of active IgA nephropathy in…18. 4. 2020 Source: Sartans in the Treatment of Hypertension
Impact of Lifestyle on the Benefit of Pharmacotherapy for Hypertension and Dyslipidemia
Antihypertensive and hypolipidemic therapy reduces the risk of cardiovascular (CV) diseases. Observational studies have shown that factors of a healthy lifestyle also have this influence. But is the…18. 4. 2020 Source: Sartans in the Treatment of Hypertension
Incontinence as a Consequence of Surgical Procedure on the Prostate
Despite the advent of new surgical methods, urinary incontinence after prostate procedures remains a clinically significant iatrogenic complication. For patients, it represents a significant stress…17. 4. 2020 Source: Incontinence
6 Years Follow-Up of Patients with Breast Cancer in the APHINITY Study
The primary analysis of results from the APHINITY clinical trial supported the combined anti-HER2 treatment with trastuzumab and pertuzumab in combination with chemotherapy in patients with early…17. 4. 2020 Source: Breast Carcinoma
Idiopathic Pulmonary Fibrosis from the Perspective of an Outpatient Pulmonologist
Idiopathic pulmonary fibrosis represents a rare disease of lung tissue with an as-yet-unexplained etiology. In the framework of differential diagnosis, it is necessary to consider the disease, as…16. 4. 2020 Source: Pulmonary Fibrosis
Thinking About Idiopathic Pulmonary Fibrosis?
Idiopathic pulmonary fibrosis (IPF) is one of the most prognostically severe and difficult-to-treat lung diseases. It affects about 5 million people worldwide, with an estimated incidence in the…16. 4. 2020 Source: Pulmonary Fibrosis
American Heart Association: Side Effects of Statins Overview and Context
The American Heart Association (AHA) report provides an updated summary of knowledge on the safety of statin use. Despite warnings appearing in professional literature and general media, it assures…15. 4. 2020 Source: Cardiovascular Risks
Third Generation Targeted Therapy for ROS1-Positive NSCLC
The potent third-generation tyrosine kinase inhibitor, lorlatinib, has shown activity in preclinical studies against nearly all known mutations in the ALK and ROS1 genes that lead to resistance to…15. 4. 2020 Source: Genetic Profile and Treatment of NSCLC
Key Role of HRCT in Diagnosing Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis is often an unjustly overlooked disease. The truth is that it is a rare disease, but the prognosis for patients is very poor. To improve quality of life and chances of…15. 4. 2020 Source: Pulmonary Fibrosis
The Choice of Incontinence Aids Matters − But How Not to Get Lost Among Them?
Despite significant advances in medicine, a large number of patients still struggle with incontinence, which limits their comfort and reduces their quality of life. If treatment options have been…14. 4. 2020 Source: Incontinence
Prevalence of Diabetics Among Patients with COVID-19 and the Impact of DM on the Course of Infection
Italian authors published the results of a meta-analysis of studies at the end of March, assessing the prevalence of diabetes among individuals infected with SARS-CoV2 and the impact of diabetes on…14. 4. 2020 Source: Modern Treatment of Diabetes
Idiopathic Pulmonary Fibrosis: Rare Disease with Severe Prognosis
Idiopathic pulmonary fibrosis (IPF) represents a diagnostic and therapeutic challenge. This rare diffuse primary fibroproliferative involvement of lung tissue is characterized by progressive…14. 4. 2020 Source: Pulmonary Fibrosis
Impact of Empagliflozin on the Risk of Cardiovascular Death and Need for Hospitalization Due to Heart Failure
In the EMPA-REG OUTCOME study, empagliflozin reduced the risk of cardiovascular death and the number of hospitalizations due to heart failure in patients with type 2 diabetes (T2DM) who had confirmed...10. 4. 2020 Source: Diabetes
Domestic application of biological asthma treatment improves quality of life and reduces doctor visits
The benefits of the possibility of home application of omalizumab, a monoclonal antibody indicated for patients with severe allergic asthma, are summarized by Dr. Jakub Novosad, Ph.D., from the…9. 4. 2020 Source: Asthma under controlLogin#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
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