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Incontinence Dermatitis -⁠ Common, Yet Often Overlooked Diagnosis

21. 4. 2020 Source: Incontinence

Incontinence dermatitis is an inflammatory skin reaction with a prevalence between 3 and 25%, caused by prolonged skin contact with urine or feces. It is classified among contact irritant dermatitis. It causes significant discomfort to patients and can also require difficult and prolonged treatment.

Through Obstacles to the Stars –⁠ Path to Developing a Healthy Gut Microbiota in Children: What Blocks It and What Helps?

The gut microbiota is acquired by an individual during the first 2 years of life. The main source is the mother’s microbiota. Obstacles to the formation of an adequate microbiota include…

21. 4. 2020 Source: GI, colic and microbiome

FOLFOXIRI and Panitumumab in mCRC Treatment –⁠ Improvement in Treatment Response and Metastasis Resectability

For patients with metastatic colorectal cancer (mCRC) who are able to undergo intensive treatment, the FOLFOX (5-fluorouracil/leucovorin, oxaliplatin) or FOLFIRI (5-fluorouracil/leucovorin,…

21. 4. 2020 Source: Colorectal Cancer

Early Cytoreductive Treatment Delays Onset of Symptoms Associated with Metastatic Colorectal Carcinoma

Managing symptoms associated with advanced cancer has a significant impact on patients' quality of life and influences decisions about appropriate therapy for an individual patient. An international…

21. 4. 2020 Source: Colorectal Cancer

Itoprid helps diabetics with reduced gastrointestinal motility improve diabetes control

The prokinetic itoprid led not only to the alleviation of gastroparesis symptoms and an improvement in quality of life in a prospective multicenter observational study on patients with diabetes and…

21. 4. 2020 Source: Gastrointestinal Treatment

krk vyšetření konzultace jícen lékař medicína

Effect of Itopride on Esophageal Motility and Lower Esophageal Sphincter Function

Itopride is a prokinetic used in the therapy of functional non-ulcerous upper dyspeptic difficulties. The mechanism of action involves inhibition of acetylcholinesterase and antagonism at dopamine D2…

21. 4. 2020 Source: Gastrointestinal Treatment

Can tofacitinib have a positive impact on the mental stress of patients with rheumatoid arthritis?

In the population of patients with rheumatoid arthritis (RA), there is a higher incidence of depression and anxiety compared to the healthy population. These psychiatric comorbidities can lead to a…

21. 4. 2020 Source: Arthritis

Educational Quiz (For Downtime)

The following quiz has been prepared for you as an activity for relaxation and unwinding from today's hectic days. In an easy manner, it will refresh your knowledge about immune cells and may even offer...

20. 4. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Significant Reduction in the Extent and Intensity of Psoriasis After Initiating Therapy with Skin Foam −⁠ Case Study

A case study from the Clinic of Skin and Venereal Diseases, Faculty of Medicine, Palacky University, and University Hospital Olomouc, describes the treatment course of psoriasis in a young patient…

20. 4. 2020 Source: Topical Treatment of Psoriasis

Brodalumab –⁠ 5 Years of Data on Efficacy, Safety, and Quality of Life Improvement in Plaque Psoriasis

Chronic inflammatory diseases, including psoriasis, require therapeutic approaches that maintain efficacy and tolerability even during long-term treatment. One such modern modality is brodalumab, a…

20. 4. 2020 Source: Topical Treatment of Psoriasis

Impact of Candesartan on Achieving Remission in Patients with Active IgA Nephropathy

IgA nephropathy is the most common glomerulonephritis worldwide and in the Czech Republic. The effect of candesartan (an angiotensin receptor blocker) on the remission of active IgA nephropathy in…

18. 4. 2020 Source: Sartans in the Treatment of Hypertension

zdravý životní styl sport jídlo pohyb cvičení medicína

Impact of Lifestyle on the Benefit of Pharmacotherapy for Hypertension and Dyslipidemia

Antihypertensive and hypolipidemic therapy reduces the risk of cardiovascular (CV) diseases. Observational studies have shown that factors of a healthy lifestyle also have this influence. But is the…

18. 4. 2020 Source: Sartans in the Treatment of Hypertension

Incontinence as a Consequence of Surgical Procedure on the Prostate

Despite the advent of new surgical methods, urinary incontinence after prostate procedures remains a clinically significant iatrogenic complication. For patients, it represents a significant stress…

17. 4. 2020 Source: Incontinence

6 Years Follow-Up of Patients with Breast Cancer in the APHINITY Study

The primary analysis of results from the APHINITY clinical trial supported the combined anti-HER2 treatment with trastuzumab and pertuzumab in combination with chemotherapy in patients with early…

17. 4. 2020 Source: Breast Carcinoma

Idiopathic Pulmonary Fibrosis from the Perspective of an Outpatient Pulmonologist

Idiopathic pulmonary fibrosis represents a rare disease of lung tissue with an as-yet-unexplained etiology. In the framework of differential diagnosis, it is necessary to consider the disease, as…

16. 4. 2020 Source: Pulmonary Fibrosis

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