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The impact of nutrition on the results of IVF/ET infertility treatments


Authors: M. Sviteková;  K. Čadová;  I. Crha;  P. Ventruba;  J. Žáková
Authors‘ workplace: LF MU a FN Brno ;  Gynekologicko-porodnická klinika
Published in: Prakt Gyn 2010; 14(2): 85-88
Category: Retrospective Study

Overview

Objectives:
Disorders of nutrition have an important impact on the body metabolism and gonadal function. They can contribute to infertility and to pregnancy complications. The aim of this study was to evaluate the impact of BMI on the results of IVF/ICSI cycles in women treated at the Centre of Assisted Reproduction, Department of Gynaecology and Obstetrics from 2005 to 2007. Name of workplace: The Centre of Assisted Reproduction CAR 01 Brno, Department of Obstetrics and Gynaecology, Masaryk University in Brno, Obilní trh 11, 602 00 Brno. Material and methods: A retrospective study aimed to evaluate the impact of BMI on the results of in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) cycles of infertile women treated at the CAR between 2005 and 2007. Women were divided into 5 groups according to their BMI: group A (underweight women, i.e. BMI ≤ 18), group B (women with normal nutrition status, i.e. BMI > 19 a ≤ 24), group C (overweight women, i.e. BMI > 25 and ≤ 30), group D (obese women, i.e. BMI > 30 and ≤ 35), group E (women with extreme obesity, i.e. BMI > 35). Ovarian stimulation, cycle monitoring and other assisted reproduction procedures were performed according to the clinic standards. Statistical analysis was performed using the χ² test. Results: 1,067 women participated in the study, the mean age was 31.8 ± 4.4 years. There were 120 women in group A, 726 in group B, 164 in group C, 39 in group D and 18 women in group E. Pregnancy rate for the entire group was 34.7 %. Significantly lower (p = 0.01) pregnancy rates compared to group B (36.4%) were found in groups A (24.1 %), D (22.3 %) and E (18.5 %). No significant differences were found with respect to age, number of oocytes gained and the quality and number of transferred embryos. Conclusion: The study identified significant decrease of pregnancy rate in women with obesity and malnutrition.

Key words:
nutrition – BMI – pregnancy rate – infertility – IVF


Sources

1. Bongain A, Isnard V, Gillet JY. Excés pondéral en gynécologie et obstétrique. CNGOF 2005: 45–118.

2. Fedorcsak P, Dale PO, Storeng R et al. Impact of overweight and underweight on assisted reproduction treatment. Hum Reprod 2004; 19(11): 2523–2528.3. Krajčovičová R, Hudeček R. Nadváha a reprodukční funkce ženy. Prakt Gyn 2008; 12(2): 109–116.

4. Ku SY, Kim SD, Jee BC et al. Clinical efficacy of body mass index as predictor of in vitro fertilisation and embryo transfer outcomes. J Korean Med Sci 2006; 21(2): 300–303.

5. Rob L, Martan A, Citterbart K et al. Gynekologie. Galén 2008: 149–179.

6. Řežábek K. Asistovaná reprodukce. Praha: Maxdorf 2008: 120.

7. The ESHRE Capri Workshop Group. Nutrition and reproduction in women. Hum Reprod Update 2006; 12(3): 193–207.

8. Vašičková Z. Obezita v gynekologii a porodnictví. Prakt Gyn 2003; 3(7): 16–20.

9. Ventruba P, Žáková J, Crha I et al. Intracytoplasmatická injekce spermie do oocytu a asistovaný hatching – mikromanipulační techniky zvyšující úspěšnost programu fertilizace in vitro. Prakt Gyn 1997; 1: 14–25.

10. Wang JX, Davies M, Norman RJ. Body mass and probability of pregnancy during assisted reproduction treatment: retrospective study. BMJ 2000; 321(7272): 1320–1321.

11. Zvára K. Biostatistika. Praha: Karolinum 2006: 213.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Topics Journals
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