The impact of nutrition on the results of IVF/ET infertility treatments
Authors:
M. Sviteková; K. Čadová; I. Crha; P. Ventruba; J. Žáková
Authors‘ workplace:
LF MU a FN Brno
; Gynekologicko-porodnická klinika
Published in:
Prakt Gyn 2010; 14(2): 85-88
Category:
Retrospective Study
Overview
Objectives:
Disorders of nutrition have an important impact on the body metabolism and gonadal function. They can contribute to infertility and to pregnancy complications. The aim of this study was to evaluate the impact of BMI on the results of IVF/ICSI cycles in women treated at the Centre of Assisted Reproduction, Department of Gynaecology and Obstetrics from 2005 to 2007. Name of workplace: The Centre of Assisted Reproduction CAR 01 Brno, Department of Obstetrics and Gynaecology, Masaryk University in Brno, Obilní trh 11, 602 00 Brno. Material and methods: A retrospective study aimed to evaluate the impact of BMI on the results of in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) cycles of infertile women treated at the CAR between 2005 and 2007. Women were divided into 5 groups according to their BMI: group A (underweight women, i.e. BMI ≤ 18), group B (women with normal nutrition status, i.e. BMI > 19 a ≤ 24), group C (overweight women, i.e. BMI > 25 and ≤ 30), group D (obese women, i.e. BMI > 30 and ≤ 35), group E (women with extreme obesity, i.e. BMI > 35). Ovarian stimulation, cycle monitoring and other assisted reproduction procedures were performed according to the clinic standards. Statistical analysis was performed using the χ² test. Results: 1,067 women participated in the study, the mean age was 31.8 ± 4.4 years. There were 120 women in group A, 726 in group B, 164 in group C, 39 in group D and 18 women in group E. Pregnancy rate for the entire group was 34.7 %. Significantly lower (p = 0.01) pregnancy rates compared to group B (36.4%) were found in groups A (24.1 %), D (22.3 %) and E (18.5 %). No significant differences were found with respect to age, number of oocytes gained and the quality and number of transferred embryos. Conclusion: The study identified significant decrease of pregnancy rate in women with obesity and malnutrition.
Key words:
nutrition – BMI – pregnancy rate – infertility – IVF
Sources
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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
2010 Issue 2
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