Surgical treatment of liver metastases of gastric cancer
Authors:
J. Šimša 1; M. Levý 1; J. Vedralová 2
Authors‘ workplace:
Chirurgická klinika 1. LF UK a Thomayerovy nemocnice, Praha, přednosta: Doc. MUDr. J. Šimša, Ph. D.
1; Oddělení patologie a národní referenční laboratoř TSE-CJN TN, Praha, primář: MUDr. F. Koukolík, DrSc.
2
Published in:
Rozhl. Chir., 2012, roč. 91, č. 8, s. 417-421.
Category:
Review
Práce je publikována při příležitosti významného životního jubilea prof. MUDr. Jiřího Hocha, CSc., přednosty Chirurgické kliniky 2. LF UK a FN Motol v Praze.
Overview
Introduction:
Gastric cancer, despite of its decreasing incidence, remains a serious medical problem. Many patients see a specialist as late as in the IVth stage of the disease with peritoneal seedings or liver metastases. Liver resection for gastric cancer metastases remains to be a controversial issue.
Material and methods:
The aim of this study is to present, through our case report and literature review, the current opinions on liver resections for metastatic gastric cancer.
Results:
Based on our experience and review of the Medline literature of the last five years, we would like to present the current trends in this field.
Conclusions:
Liver resection for gastric cancer metastases remains a controversial topic. However, in a very carefully selected group of patients, improved survival can be reached by combining liver resection and modern systemic treatment.
Key words:
gastric cancer – liver metastasis – surgical treatment
Sources
1. Zhoubné novotvary 2009, Národní onkologický registr ČR, ÚZIS, 2012.
2. Nakamura R, Saikawa Y, Kumagai K et al. A patient with gastric cancer and liver metastases successfully treated with combination chemotherapy including S-1. Int J Clin Oncol 2007;12(4):295–9.
3. Matsuno H, Hirao M, Tanaka E et al. A long-term survival case of liver metastases from gastric cancer treated with radiofrequency ablation and radiotherapy. Gan To Kagaku Ryoho 201; 38(12):1957–9.
4. Cheon SH, Rha SY, Jeung HC et al. Survival benefit of combined curative resection of the stomach (D2 resection) and liver in gastric cancer patients with liver metastases. Ann Oncol 2008;19(6):1146–53.
5. Saiura A, Umekita N, Inoue S et al. Clinicopathological features and outcome of hepatic resection for liver metastasis from gastric cancer. Hepatogastroenterology 2002;49(46):1062–5.
6. Ueda K, Iwahashi M, Nakamori M et al. Analysis of the prognostic factors and evaluation of surgical treatment for synchronous liver metastases form gastric cancer. Langenbecks Arch Surg 2009;394(4):647–53.
7. Morise Z, Sugioka A, Hoshimoto S et al. The role of hepatectomy for patients with liver metastases of gastric cancer. Hepatogastroenterology 2008;55(85):1238–41.
8. Dittmar Y, Altendorf-Hofmann A, Rauchfuss F et al. Resection of liver metastases is beneficial in patients with gastric cancer: report on 15 cases and review of literature. Gastric Cancer 2012;15(2):131–6.
9. Makino H, Kunisaki C, Izumisawa Y et al. Indication for hepatic resection in the treatment of liver metastases from gastric cancer. Anticancer Res 2010;30(6):2367–76.
10. Nomura T, Kamio Y, Takasu N et al. Intrahepatic micrometastases around liver metastases from gastric cancer. J Hepatobiliary Pancreat Surg 2009;16(4):493–501.
11. Wechsler J, Penka I. Jaterní metastázy nekolorektálního původu v Čapov I a kol. Chirurgie orgánových metastáz. Galén, 2008:94.
Labels
Surgery Orthopaedics Trauma surgeryArticle was published in
Perspectives in Surgery
2012 Issue 8
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