Anti- biotic Prophylaxis in Urology

Czech version

Authors: M. Broďák; J. Pacovsky; J. Košina; L. Holub; P. Navrátil; M. Romžová; M. Louda; P. Morávek
Authors‘ workplace: Urologická klinika FN a LF UK Hradec Králové, přednosta: MUDr. Miloš Broďák, Ph. D.
Published in: Rozhl. Chir., 2009, roč. 88, č. 7, s. 357-363.
Category: Monothematic special - Original

Overview

Antibiotic prophylaxis is an important measure aimed at reduction of infectious complications after urologic procedures. The goal of this prospective study is assessment of the efficacy, safety and cost of short-time antibiotic prophylaxis before planned urologic surgery. Uncomplicated cystoscopy, urodynamic examination and ESWL were performed without antibiotic prophylaxis. Oral quinolones were effective in prostate biopsy. In open, laparoscopic or endoscopic surgery intravenous prophylaxis by cephalosporins had excellent efficacy. All types of prophylaxes were very safe and without adverse effects, and could be applied at low economic cost.

Key words:
antibiotic prophylaxis – infectious complications – urologic procedures

Sources

1. Matsumoto, T., Kiyota, H., Matsukawa, M, Yasuda, M., Arakawa, S., Monden, K. Japanese guidelines for prevention of perioperative infection in urological field. Int. J. Urol., 2007; 14: 890–909.

2. Mangram, A. J., Horan, T. C., Pearson, M. L., Silver, L. C., Narcis, W. R. Guideline for Prevention of Surgical Site Infection. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am. J. Infect. Control., 1999; 27: 97–132.

3. Haridas, M., Malagoni, N. A. Predictive factors for surgical site infection in generál surgery. Surgery, 2008; 144: 496–501.

4. Hamasuna, R., Betsunoh, H., Sueyoshi, T., Yakushiji, K., Tsukino, H., Nagano, M., Takehara, T. Osada Y Bacteria of preoperative urinary tract infections contaminate the surgical fields and develop surgical site infections in urological operations. Int. J. Urol., 2004, 2004; 11: 941–947.

5. Schaeffer, A. J., Montorsi, F., Scattoni, V., Perroncel, R., Song, J., Haverstock, D. C., Pertel, P. E. Comparison of a 3-day with a 1-day regimen of an extended-release formulation of ciprofloxacin as antimicrobial prophylaxis for patients undergoing transrectal needle biopsy of the prostate. BJU Int., 2007; 100: 51–57.

6. Aron, M., Rajeen, T. P., Gupta, N. P. Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int., 2000; 85: 492–494.

7. Isen, K., Kupeli, B., Sinik, Z., Sozen, S., Bozkirli, I. Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral flouroquinolone versus trimethoprim-sulfamethoxazole. Int. Urol. Nephrol., 1999; 31: 491–495.

8. Kapoor, D. A., Klimberg, I. W., Malek, G. H., Wegenke, J. D., Cox, C. E., Patterson, A. L., Graham, E., Echols, R. M., Whalen, E., Kowalsky, S. F. Single-dose oral ciprofloxacin versus placebo for prophylaxis during transrectal prostate biopsy. Urology, 1998; 52: 552–558.

9. Lindstedt, S., Lindstrom, U., Ljunggren, E., Wullt, B., Grabe, M. Single-dose antibiotic prophylaxis in core prostate biopsy: Impact of timing and identification of risk factors. Eur. Urol., 2006; 50: 832–837.

10. Tobias-Machado, M., Correa, T. D., De Baros, E. L., Wroclawski, E. R. Antibiotic prophylaxis in prostate biopsy. A comparative randomized clinical assay between ciprofloxacin, norfloxacin and chloramphenicol. Int. Braz. J. Urol., 2003; 29(4): 313–319.

11. Griffith, B. C., Morey, A. F., Ali-Khan, M. M., Canby-Hagino, E., Foley, J. P., Rozanski, T. A. Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk. J. Urol., 2002; 168(3): 1021–1023.

12. Sabbagh, R., McCormack, M., Peloquin, F., Faucher, R., Perreault, J. P., Perrotte, P., Karakiewics, P. I., Saad, F. A prospective randomized trial of 1-day versus 3-day antibiotic prophylaxis for transrectal ultrasound guided prostate biopsy. Can. J. Urol., 2004; 11: 2216–2219.

13. Larsson, P., Norming, U., Tornblom, M., Gustafsson, O. Antibiotic prophylaxis for prostate biopsy: benefits and costs. Prostate Cancer Prostatic Dis., 1999; 2: 88–90.

14. Aus, G., Ahlgren, G., Bergdahl, S., Hugosson, J. Infection after transrectal core biopsies of the prostate – risk factors and antibiotic prophylaxis. Br. J. Urol., 1996; 77(6): 851–855.

15. Vivien, A., Lazard, T., Rauss, A., Paiane, M. J., Bonnet, F. Infection after transurethral resection of the prostate: variation among centers and correlation with a long-lasting surgical procedure. Association pour la Recherche en Anesthésie-Réanimation. Eur. Urol., 1998; 33(4): 365–369.

16. Girou, E., Rioux, C, Brun-Buisson, C, Lobel, B. Infection Committee of the French Association of Urology The postoperative bacteriuria score: a new way to predict nosocomial infection after prostate surgery. Infect Control Hosp. Epidemiol., 2006; 27(8): 847–854.

17. Schmiedl, S., Thurmann, P. A., Roth, S. Antibiotic prophylaxis for patients with transurethral resection of the prostate (TUR-P). Urologe A, 2009; 48 (1) :66–72.

18. Quing, W., Jianchen, W., MacDonald, R., Monga, M., Wilt, T. J. Antibiotic prophylaxis for transurethral prostatic resection in men with preoperative urine containing less than 100,000 bacteriaper ml: a systemic review. J. Urol., 2005; 173: 1175–1181.

19. Bery, A., Barrat, A. Prophylactic use in transurethral prostatic resection: a metanalysis. J. Urol., 2002; 167: 571–577.

20. Wagenlehner, F. M. E., Wagenlehner, C, Schnizel, S., Naber, K. G. Prospective randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/ sulfamethoxasole versus a control group in patients undergoing TUR of the prostate. Eur. Urol., 2005; 47: 549–556.

21. Bootsma, A. M., Laguna Pes, M. P., Geerligs, S. E., Goosens, A. Antibiotic prophylaxis in urologie procedures: a systematic review. Eur. Urol., 2008; 54(6): 1270–1286.

22. Claes, H., Vandeursen, R., Baert, L. Amoxycillin/clavulanate prophylaxis for extracorporeal shock wave lithotripsy – a comparative study. J. Antimicrob. Chemother., 1989; 24 (suppl. B): 217–220.

23. Charton, M., Vallancien, G., Veillon, B., Prapotnich, D., Mombet, A., Brisset, J. M. Use of antibiotics in the conjunction with extracorporeal lithotripsy. Eur. Urol., 1990; 17: 134–138.

24. Bierkens, A. F., Hendrix, A. J., Ezz el Din, K. E., de la Rosette, J. J., Horrevorts, A., Doesburg, W., Debruyne, F. M. The value of antibiotic prophylaxis during extracorporeal shock wave lithotripsy in the prevention of urinary tract infections in patients with urine pro ven sterile prior treatment. Eur. Urol., 1997; 31: 30–35.

25. Deliveliotis, C., Giftopoulos, A., Koutsokalis, G., Raptidis, G., Kostakopoulos, A. The necessity of prophylactic antibiotics during extracorporeal shock wave lithotripsy. Int. Urol. Nephrol., 1997; 29: 517–521.

26. Ilker, Y., Turkeri, L. N., Korten, V., Tarcan, T., Akdas, A. Antimicrobial prophylaxis in management of urinary tract stones by extracorporeal shock-wave lithotripsy: is it necessary? Urology, 1995; 46: 165–167.

27. Lugg, J., Lettieri, J., Stass, H., Agarwal, V. Determination of the concentration of ciprofloxacin in prostate tissue following administration of a single, 1000 mg, extended-release dose. J. Chemother., 2008; 20: 213–218.

28. Delavierre, D., Huiban, B., Fournier, G., Le, G. G., Tande, D., Mangin, P. The value of antibiotic prophylaxis in transurethral resection of bladder tumors. Apropos of 61 cases. Prog. Urol., 1993; 3: 577–582.

29. MacDermott, J. P., Swing, R. E., Somerville, J. F., Gray, B. K. Cephradine prophylaxis in transurethral procedures for carcinoma of the bladder. Br. J. Urol., 1988; 62(2): 136–139.

30. Klimerg, I. W., Malek, G. H., Cox, C. E., Patterson, A. L., Whalen, E., Kowalsky, S. F., Echols, R. M. Single-dose oral ciprofloxain compared with cefotaxim and placebo for prophylaxis during transurethral surgery. J. Antimicrob. Chemother., 1993; 43(suppl A): 77–84.

31. Yamamoto, S., Kunishima, Y., Kanamaru, S., Ito, N. et al. A multi-center prospective study for antibiotic prophylaxis to prevent perioperative infections in urologie surgery. Hinyokika Kiyo, 2004; 50(10): 673–683.

32. Kanamaru, S., Terai, A., Ishitova, S., Kunishima, Y. Assessment of a protocol for prophylactic antibiotics to prevent perioperative infection in urological surgery: a preliminary study. Int. J. Urol., 2004; 11(6): 355–363.

33. Takeyama, K., Shimizu, T., Mutoh, M., Nishivama, N., Kunishima, Y., Matsukawa, M., Takahashi, S., Hotta, H., Itoh, N., Tsukamoto, T. Prophylactic antimicrobial agents in urologie laparoscopic surgery: 1-day versus 3-day treatments. J. Infect. Chemother., 2004; 10(3): 168–171.

34. Stranne, J., Aus, G., Hansson, C, Lodding, P., Pileblad, E., Hugosson, J. Single-dose orally administered quinolone appears to be sufficient antibiotic prophylaxis for radical retropubic prostatectomy. Scand. J. Urol. Nephrol., 2004; 38: 143–147.

35. Takeyma, K., Takahashi, S., Maeda, T., Mutoh, M., Kunishima, Y., Matsukawa, M., Takagi, Y. Comparison of 1-day, 2-day, and 3-day administration of antimicrobial prophylaxis in radical prostatectomy. J. Infect. Chemoter., 2007; 13: 320-323.

36. Terai, A., Ichioka, K., Kohei, N., Ueda, N., Utsunomiya, N., Inoue, K. Antibiotic prophylaxis in radical prostatectomy: 1-day versus 4-day treatments. Int. J. Urol., 2006; 13: 1488–1493.

37. Charton, M., Vallancien, G., Veillon, B., Brisset, J. M. Urinary tract infection in percutaneous surgery for renal calculi. J. Urol., 1986; 135: 15–17.

38. Osman, M., Wendt-Nordahl, G., Heger, K., Michel, M. S., Alken, P., Knoll, T. Percutaneous nephrolithotomy with ultrasonography-guided renal access: experience from over 300 cases. BJU Int., 2005; 96: 875–878.

39. Dogan, H. S., Sahin, A., Cetinkaya, Y., Akdogan, B., Ozden, E., Kendi, S. Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients. J. Endourol., 2002; 16: 649–653.

40. Fourcade, R. O. antibiotic prophylaxis with cefotaxime in endoscopic extraction of upper urinary tract stones: a randomized study. The Cefotaxime Cooperative Group. J. Antimicrob. Chemother., 1990; 26 (suppl A): 77–83.

41. Knopf, H-J., Draft, H-J., Schulze, H. Perioperative antibiotic prophylaxis in ureteroscopic stone removal. Eur. Urol., 2003; 44: 115–118.