Rare Cases of Extensive Retroperitoneal Liposarcomas
Authors:
Radek Pohnán; M. Ryska; M. Kučera; P. Chmátal
Authors‘ workplace:
Chirurgická klinika 2. LF UK a ÚVN Praha, přednosta: prof. MUDr. M. Ryska, CSc.
Published in:
Rozhl. Chir., 2008, roč. 87, č. 7, s. 364-366.
Category:
Monothematic special - Original
Overview
Introduction:
Liposarcomas of the retroperitoneal area (LSRP) are rare mesenchymal tumour, which are literary ranked among the retroperitoneal soft-tissue sarcomas. they can reach enormous size, while patients complains aren’t distinctive. The most common symptoms are abdominal discomfort and distention of abdominal volume with a palpable resistention. The only successful treatment of this tumor is surgical exstirpation.
Case report 1:
77-year-old patient was investigated because of gradually accruing size of the abdomen. There was a lipoid tumour in the peritoneal cavity shown by computed tomography, suspected coming out of the retroperitoneal area. During the operation we found out giant well-differentiated liposarcoma which grew from the retroperitoneal area. Postoperative period was complicated by bleeding and consequently by MOF. 14th postoperative day patient died. Dissection finding was another location of liposarcomas in the retroperitoneal area.
Case report 2:
66-year-old patient was investigated because of increasing girth. Abdominal ultrasonography and CT displayed adipoid formation which filled up most of the peritoneal cavity with compression of surrounding organs. The tumour was completely resected during operation. The patient has been followed in dispensatory for two years without any signs of recurrence of the illness.
Discussion:
Liposarcomas are the most frequent histological type among primary retroperitoneal sarcomas. Metastatic potential of LSRP is low but these tumors often recur locally. In diagnostics and in follow-up are essential CT and MRI. Successful therapy is radical resection. It could be difficult to distinguish giant well-differentiated liposarcomas from normal retroperitoneal fat. Incomplete resection is a palliation operation without chance for long survival.
Key words:
retroperitoneal liposarcomas – surgical treatment
Sources
1. Hassan, I., Park, S. Z., Donohue, J. H., et al. Operative management of primary retroperitoneal sarcomas. Ann. Surg., 2004; 239; 244–250.
2. Fletcher, C. M., Akerman, P., Cin, I., et al. Correlation between clinical pathological features and karyotype in lipomatous tumors. Am. J. Pathol., 1996; 148; 623–630
3. Singer, S., Antonescu, C., Riedel, E., et al. Histological subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcomas. Ann. Surg., 2003; 238; 358–371.
4. Becker, H. D., Hohenberger, W., Junginger, T., Schlag, P. M. Chirurgická onkologie. 1. vyd., Praha: Grada, 2005. 617–625.
5. Lewis, J. J., Leung, D., Woodruff, J. M., et al. Retroperitoneal Soft-Tissue Sarcoma: Analysis of 500 patients treated and followed at a single institution. Ann. Surg., 1998; 228; 355–365.
6. Bradley, J. C., Caplan, R. Giant retroperitoneal sarcoma: a case report and review of the management of retroperitoneal sarcomas. Am. Surg., 2002; 68; 52–56.
7. Bautista, N., Su, W., O’Connell, T. X. Retroperitoneal soft-tissue sarcomas: prognosis and treatment of primary and recurrent disease. Am. Surg., 2000; 66; 832–836.
8. Gockel, I., Oberholzer, K., Gonner, U., Mantai, S., Junginger, T. Retroperitoneal sarcomas: diagnostic and therapy. Zentralbl. Chir., 2006; 131; 223–229.
9. Neuhaus, S. J., Barry, P., Clark, M. A., et al. Surgical management of primary and recurrent retroperitoneal liposarcoma. Br. J. Surg., 2005, 92; 246–252.
10. Alldinger, I., Yang, Q., Pilarsky, C., et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients. Anticancer Res., 2006; 26; 1577–1581.
11. Vrba, R., Neoral, Č., Bohanes, T., Aujeský, R. Liposarkom retroperitonea – kazuistické sdělení. Rozhl. Chir., 2004; 83;70–72.
12. Huťan, M., Lukac, I., Poticny, V., Ondrias, F. Giant retroperitoneal liposarcomas. Rozhl. Chir., 2005; 84; 547–551.
13. Nahodil, V. Liposarkomy retroperitonea. Rozhl. Chir., 1962; 41; 91–97.
14. Nahodil, V. K otázce léčení a prognózy obrovských liposarkomů retroperitonea. Rozhl. Chir., 1969; 48; 10–13.
Labels
Surgery Orthopaedics Trauma surgeryArticle was published in
Perspectives in Surgery
2008 Issue 7
Most read in this issue
- Pectoralis Maior Tendon Rupture and Anabolic Steroids in Anamnesis – a Case Review
- Re-expansion Pulmonary Edema as a Complication of a Spontaneous Pneumothorax Drainage – a Case Review
- Rare Cases of Extensive Retroperitoneal Liposarcomas
- Stents – Paliative and Curative Management of Esophageal Conditions. Seven-Year Surgical Experience