Novel imaging methods in endoscopic diagnosis of gastrointestinal tumors
Authors:
prof. MUDr. CSc. Julius Špičák
Authors‘ workplace:
Klinika hepatogastroenterologie IKEM Praha
Published in:
Čas. Lék. čes. 2016; 155: 13-22
Category:
Review Articles
Overview
Advances in imaging, digitization and all kinds of technologies result in development of potentially efficient imaging modalities, which enable magnification to subcellular levels, color differentiation and observation of pathophysiological processes. NBI, FICE, I-scan and KFE are new commercially available modalities.
NBI is the most explored one. Its contribution has been shown in diagnosis of Barrett's neoplasia and esophageal squamous cell carcinoma and in characterization of early stomach cancer. It enables rather accurate characterization of changes in adenomatous colonic polyps; however it is not used for this purpose in clinical practice. It can demonstrate atrophy of small bowel mucosa in celiac disease, but it is not able to evaluate intraepithelial lymphocytosis. Its contribution in dysplasia detection in inflammatory bowel disease is not significant; chromoendoscopy remains the gold standard.
The use of CFE remains experimental; the routine use is limited also due to its high cost.
Keywords:
imaging, new technologies, colonoscopy, NBI, FICE, i-scan, autofluorescence, confocal endomicroscopy, neoplasia
Sources
1. Sharma P, Gupta N, Kuipers EJ et al. Advanced paging in colonoscopy and its impact on quality. Gastrointest Endosc 2014; 79: 28–36.
2. Gono K, Oni T, Yamaguchi M et al. Appearence of enhanced tissue features in narrow-band endoscopic imaging. J Biomed Opt 2004; 9: 568–577.
3. Yoshida N, Yagi N, Yanagisawa A et al. Image enhanced endoskopy for diagnosis of colorectal tumors in view of endoscopic treatment. World J Gastroenterol 2012; 4: 545–555.
4. Matsuda T, Saito Y, Fu KI et al. Does autofluorescence imaging videoendoscopy system improve the colonoscopic polyp detection rate? A pilot study. Am J Gastroenterol 2008; 103: 1926–1932.
5. Kuiper T, Aldelieste YA, Tytgat KMA et al. Automatic optical diagnosis of small colorectal lesions by laser induced autofluoroscence. Endoscopy 2015; 47: 56–62.
6. Isenberg K, Sivak MV, Chak A et al. Accuracy of endoscopic optical coherence tomography in the detection of dysplasia in Barrett esophagus: a prospective double-blinded study. Gastrointest Endosc 2005; 62: 826–831.
7. Rodriguez-Díaz E, Huang Q, Cerda SR et al. Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy. Gastrointest Endosc 2015; 81: 539–547.
8. Wood JJ, Kendall C, Hurchigs J et al. Evaluation of a confocal Raman probe for pathological diagnosis during colonoscopy. Colorectal Disease 2014; 16: 732–738.
9. Roy HK, Backman V. Spectroscopic applications in gastrointestinal endoscopy. Clin Gastroenterol Hepatol 2012; 10: 1335–1341.
10. Galloro G. High technology imaging in digestive endoscopy. World J Gastroenterol 2013; 4: 22–27.
11. Dunbar KB, Montgomery EA, Canto MI. The learning curve of in vivo confocal laser endomicroscopy for prediction of Barrett´s esofagus. Gastroenterology 2008; 134: A62−A63.
12. Goetz M, Deris I, Vieth M et al. Near red confocal imaging during minilaparoscopy: a novel rigid endomicroscope with increased imaging plane depth. J Hepatol 2010; 53: 84–90.
13. Eberl J, Jechart G, Probst A et al. Can an endocytoscope system (ECS) predict histology in neoplastic lesions? Endoscopy 2007; 39: 497–501.
14. Vila PM, Thekkek N, Klortum-Richards R et al. The use of in vivo real-time optical imaging for esophageal neoplasia. Mt Sinai J Med 2011; 78: 984–904.
15. Shavmoon A, Aharon S, Kruchik O et al. Scientific Reports 2013; 3: 1–7.
16. Sturm MB, Joshi BP, Lu S et al. Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: First in human results. Sci Transl Med 2013; 5: 184–191.
17. Xian V, McKeon F, Koy KY. Biomarkers and molecular imaging in gastrointestinal cancers. Clin Gastroenterol Hepatol 2014; 12: 126–129.
18. Li H, Li Y, Cui L et al. Monitoring pancreatic cancerogenesis by the molecular imaging of cathepsin E in vivo using confocal laser endomicroscopy. PLoS One 2014; 9: 1–12.
19. Ko KH, Han NY, Kwon CH II et al. Recent advances in molecular imaging of premalignant gastrointestinal leisions and future application for early detection of Barrett esofagus. Clin Endosc 2014; 47: 7–14.
20. Goetz M, Kiesslich R. Advances of endomicroscopy for gastrointestinal physiology and diseases. Am J Physiol Gastrointest Liver Physiol 2010; 298: G797–G806.
21. Kudo S, Hirota S, Nakajima T et al. Colorectal tumours and pit pattern. J Clin Pathol 1994; 47: 880–885.
22. van Rijn JC, Reitsma JB, Stoker J et al. Polyp miss-rate determined by tandem colonoscopy: A systematic review. Am J Gastroenterol 2006; 101: 343–350.
23. Sabbagh LC, Reveiz L, Aponte D et al. Narrow-band ligation imaging does not improve detection of colorectal polyps when compared to conventional colonoscopy: A randomized controlled trial and meta-analysis of published studies. BMC Gastroenterology 2011; 11: 100–113.
24. Yoshida N, Yagi N, Yanagisawa A et al. Image-emhanced endoscopy for diagnosis of colorectal cancer tumors in view of endoscopic treatment. World J Gasteroenterol 2012; 4: 545–555.
25. Gilani N, Stipho S, Panetta JD et al. Polyp detection trates using magnification with narrow band imaging and white light. World J Gastrointest Endosc 2015; 7: 555–562.
26. Rastogi A, Keighley J, Singh V et al. High accuracy of narrow band imaging without magnification for the real-time characterization of polyp histology and its comparison with high-definition white light endoscopy: a prospective study. Am J Gastroenterol 2009; 104: 2422–2430.
27. Tanaka S, Sano Y. Aim to unify the narrow band imaging magnifying classification for colorectal tumors current status in Japan from a summary of the consensus symposium in the 79th Annual Meeting of the Japan Gastroenterological Endoscopy Society. Dig Endosc 2011; 23 Suppl 1: 131–139.
28. Sano Y, Ikematsu H, Fu KI et al. Meshed capillary vessels by use of narrow-band imaging for differential diagnosis by use of narrow-band imaging for differential diagnosis of small colorectal polyps. Gastrointest Endosc 2009; 69: 278–283.
29. Kanao H, Tanaka S, Oka S et al. Norrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors. Gastrointest Endosc 2009; 69: 631–636.
30. Wada Y, Kashida H, Kudo SE et al. Diagnostic accuracy of pitt pattern and vascular pattern analyses in colorectal lesions. Dig Endosc 2010; 22: 192–199.
31. Cipoletta I, Bianco MA, Rotondano G et al. Endocytoscopy can identify dysplasia in aberrant crypt foci of the colorectum: A prospective in vivo study. Endoscopy 2009; 41: 129–132.
32. Dhar A, Johnson KS, Novelli MR et al. Elastic scattering spectroscopy for the diagnosis of slonic lesions: initial results of a novel optical biopsy technique. Gastrointest Endosc 2006; 63: 257–261.
33. Gomes AJ, Roy HK, Turzhitsky V et al. Rectal mucosal microvascular blood supply increase is associated with colonic neoplasia. Clin Cancer Res 2009; 15: 3110–3117.
34. Takeuchi Y, Inoue T, Hanaoka N et al. Autofluorescence imaging with a transparent hood for detection of colorectal neoplasms: a prospective, randomized trial. Gastrointest Endosc 2010; 72: 1006–1013.
35. Polglase AL, McLaren WJ, Skinner SA et al. A fluorescence confocal endomicroscope for in vivo microscopy of upper- and the lower-GI tract. Gastrointest Endosc 2005; 62: 685–695.
36. Wanders LK, East JE, Uitentuis SE et al. Diagnostic performance of narrowed spectrum endoscopy, autofluorescence imaging, and confocal laser endomicroscopy for optical diagnosis of colonic polyps: a meta-analysis. Lancet Oncol 2013; 14: 1337–1347.
37. Omata F, Ohde S, Deshpande GA et al. Image-enhanced, chromo, and cap-assisted colonoscopy for improving adenoma/neoplasia detection rate: A systematic review and metaanalysis. Scand J Gastroenterol 2014; 49: 222–237.
38. Kamiňski MF, Hassan C, Bisschops R et al. Advanced imaging for detection and differentiation of colorectal neoplasia: ESGE guideline. Endoscopy 2014; 46: 435–449.
39. Dekker E, van den Broek FJ, Reitsma JB et al. Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patiens with longstanding ulcerative colitis. Endoscopy 2007; 132: 874–882.
40. van den Broek FJC. Fockens P, van Eeden S et al. Narrow-band imaging versus high-definition endoscopy for the diagnosis of neoplasia in ulcerative colitis. Endoscopy 2011; 43: 108–115.
41. Pellisé M, Lopéz-Cerón M, Rodriguez de Miguel C et al. Narrow-band imaging as an alternative to chroendoscopy for the detection of dysplasia in long-standing inflammatory bowel disease: a prospective, randomized, crossover study. Gastrointest Endosc 2011; 74: 840–848.
42. Leifeld L, Rogier G, Stallmach A et al. White-light or narrow-band imaging colonoscopy in surveillance of ulcerative colitis: a prospective multicenter study. Clin Gastroenterol Hepatol 2015; 13: 1776–1781.
43. Watanabe O, Ando T, Maeda O et al. Confocal endomicroscopy in patiens with ulcerative colitis. J Gastroenterol Hepatol 2008; 23 Suppl 2: S286–S290.
44. Kiesslich R, Goetz M, Lammersdorf K et al. Chromoendoscopy guided endmicroscopy increases the diagnostic field of intraepithelial neoplasia in ulcerative colitis. Gastroenterology 2007; 132: 874–884.
45. van den Broek FJ, van Eeden S, Stokkers PC et al. Pilot study of probe-based confocal endomicroscopy during colonoscopic surveillance of patients with longstanding ulcerative solitis. Endoscopy 2011; 43: 116–122.
46. Neumann H, Vieth M, Arreya R et al. Assessment of Crohn disease activity by confocal laser endomicroscopy. Inflamm Bowel Dis 2012; 18: 2261–2269.
47. Hurlestone DP, Thomson M, Brown S et al. Confocal endomicroscopy in ulcerative colitis: differentianting dyplasia associated lesional mass and adenoma-like mass. Clin Gastroenterol Hepatol 2007; 5: 2535–1541.
48. Kiesslich R, Duckworth CA, Moussata D et al. Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut 2012; 61: 1146–1153.
49. Gabbani T, Manetti N, Bonanomi AG et al. New endoscopic paging techniques in surveillance of inflammatory bowel disease. World J Gastroenterol Endosc 2015; 7: 230–236.
50. Sharma P, Wani S, Bansal A et al. A feasibility trial of narrow band uimaging endoscopoy in patiens with gastroesophageal reflux disease. Gastroenterology 2007; 133: 454–464.
51. Mannath J, Subramanian V, Hawkey CJ et al. Narrow band imaging for characterization of high grade dysplasia and specialized intestinal metaplasia in Barretts esofagus: a metaanalysis. Endoscopy 2010; 42: 351–359.
52. Vila PM, Thekkek N, Richards-Kortum R et al. The use in vivo real-time optical imaging for esophageal neoplasia. Mt Sinai J Med 2011; 78: 894–904.
53. Kim KO, Ku YS. Is image-enhanced endoscopy useful for the diagnosis and treatment of gastrointestinal tumor? Clin Endosc 2013; 46: 246–250.
54. Kara MA, Peters FP, Ten Kate FVW et al. Endoscopic video autofluorescence imaging may improve the detection of early neoplasia in patiens with Barrett´s neoplasia. Gastrointest Endosc 2005; 61: 679–685.
55. Jin NY, Wang K, Wei SQ et al. Diagnostic value of autofluorescence imaging combined with narrow band paging in intraepithelial neoplasia of Barrett's esophagus. J Buon 2015; 20: 399–405.
56. Song J, Zhang J, Wang J et al. Meta-anallysis of the effects of endoscopy with narrow band imaging in detecting dysplasia in Barrett´s esophagus. Dis Esophagus 2015; 28: 560–566.
57. Qiu L, Pleskow D, Chuttani R et al. Multispectral scanning durin endoscopy guides biopsy of dysplasia in Barrett's esofagus. Nat Med 2010; 16: 603–606.
58. Konda V, Banerjee S, Barth BA et al. Enhanced imaging in the GI tract: Spectroscopy and optical coherence tomography. Gastrointest Endosc 2013; 78: 568–573.
59. Isenberg G, Sivak MV, Chak A et al. Accuracy of endoscopic optical coherence tomography in the detection of dysplasia in Barrett's esophagus: a prospective, double-blinded study. Gastrointest Endosc 2005; 62: 825–831.
60. Tsai TH, Zhou C, Tao YK et al. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esofagus radiofrequency ablation response (with videos). Gastrointest Endosc 2012; 76: 1104–1112.
61. Zhou C, Tsai TH, Lee HC et al. Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos). Gastrointest Endosc 2012; 76: 32–40.
62. Kiesslich R, Gossner L, Goetz M et al. In vivo histology of Barrett´s esofagus and associated neoplasia by confocal laser endomicroscopy. Clin Gastroenterol Hepatol 2006; 4: 979–987.
63. Dunbar KB, Okolo P 3rd, Montgomery E et al. Confocal laser endomicroscopy in Barrett´s esofagus and endoscopically inapparent Barrett's neoplasia: a prospective, randomized, double-blind, controlled crossover trial. Gastrointest Endosc 2009; 70: 645–654.
64. Nguyen VX, Nguyen CC, De Petris G et al. Confocal endomicrolscopy (CEM) improves efficiency of Barrett surveillance. J Interv Gastroenterol 2012; 2: 61–65.
65. Muldoon TJ, Thekkek N, Roblyyer D et al. Evaluation of quantitative image analysis criterias for the high-resolution microsendoscopic detection of neoplasia in Barrett's esofagus. J Biomed Opt 2010; 15: 026–027.
66. Inoue H, Honda T, Nagai K et al. Ultra-high magnification endoscopic observation of carcinoma in situ of he esofagus. Dig Endosc 1997; 9: 16–18.
67. Arima M, Tada M, Arima H. Evaluation of microvascular patterns of superficial esophageal cancers by magnifying endoscopy. Esophagus 2005; 2: 191–197.
68. Fujishiro M, Takubo K, Sato Y et al. Potential and present limitation of endocytoscopy in the diagnosis of esophageal squamous cell carcinoma: a multicenter ex vivo pilot study. Gastrointest Endosc 2007; 66: 551–555.
69. Iguchi Y, Niwa Y, Miyahara R et al. Pilot study on confocal endomicroscopy for determination of the depth of squamous cell esophageal cancer in vivo. J Gastroenterol Hepatol 2009; 24: 1733–1739.
70. Yokoyama A, Inoue H, Minami H et al. Novel narrow-band imaing magnifying endoscopic classification for early gastric cancer. Dig Liver Dis 2010; 42: 704–708.
71. Yao K, Iwashita A, Kikuchi Y et al. Novel zoom endoscopy technics for visualising the microvascular architecture in gastric mucosa. Clin Gastroenterol Hepatol 2005; 3 (Suppl 1): S233–S236.
72. Li WB, Zuo XL, Gu XM et al. Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy. Surg Endosc 2009; 24: 517–524.
73. Wang P, Ji R, Yu T et al. Classification of histological severity of Helicobacter pylori. Associated gastritis by confocal laser endomicroscopy. World J Gastroenterol 2010; 16: 5203–5210.
74. Meining A, Shah R, Slivka A et al. Classification of probe-based confocal laser endomicroscopy findings in pancreatobiliary strictures. Endoscopy 2012; 44: 251–257.
75. Nakai Y, Isayama H, Shinoura S et al. Confocal laser endomicroscopy in gastrointestinal and pancreatobiliary diseases. Dig Endosc 2014; 26 Suppl 1: 86–94.
76. Tringali A, Lemmers A, Meves V et al. Intraductal biliopancreatic imaging: European Society of Gastrointestinal Endoscopy (ESGE) technology review. Endoscopy 2015; 47: 739–753.
77. Konda VA, Meining A, Jamil LH et al. A pilot study of in vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy under endosonographic guidance. Endoscopy 2013; 45: 1006–1013.
78. Nakai Y, Iwashita T, Park DH et al. Diagnosis of pancreatic cysts: EUS-guided, through-the-needle confocal laser induced endomicroscopy and cystoskopy trial: DETECT study. Gastrointest Endosc 2015; 81: 1204–2015.
79. Leing RW, Nguyen NQ, Meredith CH et al. In vivo confocal endomicroscopy in the diagnosis and evaluation of coeliac disease. Gastroenterology 2008; 135: 1870–1876.
80. Venkatesh K, Abou-Teleb A, Cohen M et al. Role of confocal endomicroscopy in the diagnosis of celiac disease. J Pediatr Gastroenterol Nutr 2010; 51: 274–279.
81. Günther U, Daum S, Heller F et al. Diagnostic value of confocal endomicroscopy in celiac disease. Endoscopy 2010; 42: 197–212.
82. Malard F, Mohty M. New insights for the diagnosis of gastrointestinal acute graft-versus-host disease. Mediators Inflamm 2014: 701013. doi: 10.1155/2014/701013.
83. van Rijn JC, Rewitasima JB, Stoker J et al. Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol 2006; 101: 343–350.
84. Leufkens AM, DeMarco DC, Rastogi A et al. Effect of a retrograde-viewing device on adenoma detection rate during colonoscopy: The TERRACE study. Gastrointest Endosc 2011; 73: 480–489.
85. Rubin M, Lurie L, Bose K et al. Expanding the view of a standard colonoscope with the Third Eye Panoramic Cap. World J Gastroenterol 2015; 21: 10683–10687.
86. Gralnek IM. Emerging technological advancements in colonoscopy. Dig Endosc 2015; 27: 223–231.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
Most read in this issue
- Pancreatic cancer – current effective diagnostic and therapeutic approach
- Malignant biliary obstruction
- Professor Josef Marek - octogenarian
- Foregut diseases: foregut neoplasms