News in diagnostics and treament of cardiomyopathies
Authors:
Hana Poloczková 1; Tomáš Honek 1; Anna Chaloupka 1; Lukáš Opatřil 1,2; Mária Bakošová 1; Jan Krejčí 1
Authors‘ workplace:
I. interní kardioangiologická klinika Fakultní nemocnice u sv. Anny v Brně, a Lékařské fakulty Masarykovy univerzity
1; Mezinárodní centrum klinického výzkumu Fakultní nemocnice u sv. Anny v Brně
2
Published in:
Vnitř Lék 2023; 69(2): 89-104
Category:
Main Topic
doi:
https://doi.org/10.36290/vnl.2023.016
Overview
Cardiomyopathies are defined as myocardial disorders in which the heart muscle is structurally and functionaly abnormal in the absence of a disease sufficient to cause this abnormality such as coronary artery disease, hypertension, valvular or congenital heart disease. According to the phenotype expresion cardiomyopathies are divided into dilated, hypertrophic, restrictive, arrhytmogenic and unclassified cardiomyopathies (noncompaction and tako-tsubo cardiomyopathy). The same phenotypic expression may include etiologically different forms of the disease, and at the same time phenotypic expression may change in many cardiomyopathies in the course of illness. For each type of cardiomyopathy, we further distinguish the familial (genetic) form and the acquired form. The clinical manifestation of the disease includes symptoms of heart failure, with reduced, mildly reduced or preserved ejection fraction, symptoms resulting from a number of arrhythmias and extracardiac symptoms, but in some cases symptoms may not be presented for a relatively long time. The disease can lead to significant morbidity and mortality if not detected and treated early, especially in young people who are frequently affected. Significant developments in diagnostic and treatment methods have led to an improvement in the prognosis of patients with cardiomyopathies in recent years.
Keywords:
genetic testing – heart failure – cardiomyopathy – cardiac magnetic resonance
Sources
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Další literatura u autorů a na www.casopisvnitrnilekarstvi.cz
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Diabetology Endocrinology Internal medicine CardiologyArticle was published in
Internal Medicine
2023 Issue 2
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