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Antifibrotic therapy and its indications for interstitial pulmonary fibrosis


Authors: Martina Doubková
Authors‘ workplace: Klinika nemocí plicních a TBC Fakultní nemocnice Brno a Lékařské fakulty Masarykovy univerzity Brno
Published in: Vnitř Lék 2022; 68(4): 212-215
Category: Main Topic

Overview

Idiopathic pulmonary fibrosis and chronic fibrotic interstitial lung disease with progressive phenotype are characterized by fibrotic lung parenchyma. Current antifibrotic treatment does not affect pre-existing lung parenchyma fibrosis, but prevents fibrosis progression and reduces mortality by reducing fibrotization. This work summarizes fibrotic lung processes and their treatment options.

Keywords:

idiopathic pulmonary fibrosis – nintedanib – progressive fibrosing interstitial lung diseases – pirfenidon


Sources

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Diabetology Endocrinology Internal medicine
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