Whipple disease – systemic disease with gastrointestinal manifestations
Authors:
Leoš Chrudimský
Authors‘ workplace:
Patologicko-anatomické oddělení, Nemocnice Jihlava, p. o.
Published in:
Vnitř Lék 2021; 67(E-5): 3-8
Category:
Review Articles
Overview
Whipple disease is rare, potentionally life-threatening disease with broad scale of possible symptoms and therefore wide differential diagnosis. Localized forms as well as systemic manifestations are possible. Etiological agent is bacteria Tropheryma whipplei. The most common manifestations include arthralgias, fever, diarrhea, abdominal pain, malabsorption syndrome and weight loss. In my article I present literature review and a case report of the pacient with relatively typical course of the disease.
Keywords:
malabsorption syndrome – Whipple disease – Tropheryma whipplei – intermitent fever – PAS positive macrophages – seronegative arthritis
Sources
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Labels
Diabetology Endocrinology Internal medicineArticle was published in
Internal Medicine
2021 Issue E-5
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