Anti-cancer therapy-induced metabolic syndrome

Czech version

Authors: Eva Řiháčková ¹; Lubomír Elbl ¹; Michal Řiháček ²; Mária Holická ¹; Petr Kala ¹
Authors‘ workplace: Interní kardiologická klinika, LF MU a FN Brno ¹; Biochemický ústav, LF MU, Brno ²
Published in: Vnitř Lék 2021; 67(6): 334-338
Category: Review Articles

Overview

The increasing number of long-term survivors that underwent the anti-cancer therapy faces the late treatment-related adverse effects and the increased risk of developing metabolic syndrome. This article defines the pathophysiology that underlies development of anti-cancer therapy-related metabolic syndrome and outlines the possibility of optimisation of comprehensive care focusing on prevention. Considering the preventability of metabolic syndrome, effective screening and follow-up appropriate for patients at increased risk of related adverse events should be established. Subsequently, early initiation of therapy targeting the hallmarks of metabolic syndrome may ease its manifestation in long-term perspective.

Keywords:

metabolic syndrome – oncology – anti-cancer therapy

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