Combined therapy of arterial hypertension

Czech version

Authors: H. Rosolová
Authors‘ workplace: Centrum preventivní kardiologie II. interní kliniky Lékařské fakulty UK a FN Plzeň, přednosta prof. MU Dr. Jan Filipovský, CSc.
Published in: Vnitř Lék 2013; 59(5): 366-369
Category: Review

Overview

For a successful treatment of arterial hypertension, in most patients it is necessary to prescribe at least two antihypertensive medicines. A well chosen fixed combination of antihypertensives improves lifelong compliance with treatment, another important approach to improving treatment compliance being regular education of the patient regarding the appropriateness of regular medicine taking in relation to the risks of untreated hypertension. Currently, when initiating treatment of uncomplicated hypertension, the combination of diuretics with beta‑blockers is being abandoned, especially for their metabolic adverse effects. The most frequent combination of recommended antihypertensive medicinal products is a combination of renin‑angiotensin system inhibitors, i.e. ACE inhibitors or sartans, with calcium channel blockers or diuretics. Some studies about the efficacy of this modern combined antihypertensive therapy are mentioned.

Key words:
treatment of arterial hypertension – fixed combination – compliance with treatment – telmisartan – thiazide diuretics

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