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Metabolic surgery – a new approach to the management of selected diseases


Authors: M. Fried 1,2;  K. Doležalová 1
Authors‘ workplace: Centrum pro léčbu obezity a metabolických poruch OB kliniky Praha, přednosta prof. MUDr. Martin Fried, CSc. 1;  1. lékařská fakulta UK Praha, děkan prof. MUDr. Tomáš Zima, DrSc., MBA 2
Published in: Vnitř Lék 2011; 57(4): 402-404
Category: 12th national Symposium diabetes, "Diabetes and Gastroenterology", Hradec Kralove, 4 to 5 June 2010

Overview

Treatment options for type 2 diabetes have changed dramatically in the past few years. Experimental works followed by evidence based studies proved long-term efficacy of metabolic surgery in type 2 diabetes treatment. Moreover diabetes resolution is not directly correlated with weight loss and occurs independently to it. Large literature metaanalyses showed that type 2 diabetes can be subtantially improved with metabolic surgery in about 85 % of all diabetic patients, out of which can be resolved in more than 75%. Metabolic surgery affects hormonal secretion on multiple levels namely in the small intestine. Restrictive as well as combined and malabsorptive surgical procedures have positive effect on type 2 diabetes improvement as well as on metabolic syndrome, sleep apnea syndrome and on other comorbidities.

Key words:
metabolic surgery – type 2 diabetes mellitus – surgical treatment of diabetes


Sources

1. Buchwald H, Estok R, Fahrbach K et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009; 122: 248–256.

2. Fried M et al. Bariatrická a metabolická chirurgie, nové postupy v léčbě obezity a metabolických poruch. Praha: Mladá Fronta 2011.

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8. Adami GF, Cordera R, Camerini G et al. Recovery of insulin sensitivity in obese pa­tients at short term after biliopancreatic diversion. J Surg Res 2003; 113: 217–221.

9. Scopinaro N, Adami GF, Papadia FS et al. Effects of Biliopanceratic Diversion on Type 2 Diabetes in Patients With BMI 25 to 35. Ann Surg 2011; 253: 699–703.

10. American Diabetes Association. Standards of Medical Care in Diabetes – 2010. Diabetes Care 2010; 33 (Suppl 1): S11–S61.

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Labels
Diabetology Endocrinology Internal medicine
Topics Journals
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