Can we predict mortality in elderly patients with Clostridium difficile infection?
Authors:
K. Bielaková
Published in:
Geriatrie a Gerontologie 2016, 5, č. 4: 177-180
Category:
Original Article/Study
Overview
Background:
Clostridium difficile is an important cause of nosocomial infections and especially in geriatric patients those often have lethal consequences. The goal of this study was to evaluate the risk factors for mortality in CDI patients and to construct a binary logistic regression model which describes the probability of mortality in geriatric patients suffering from CDI.
Methods:
In this retrospective study the group of 235 patients over 65 years of age with confirmed diagnoses of CDI, hospitalised at the Department of Internal Medicine, Geriatrics and General Practice, Brno, from January 2008 to December 2013, were evaluated. The examined group consisted of 148 women (63 %) and 87 men (37 %). For the diagnosis of CDI, confirmation of A and B toxins in the patients’ stool or autopsy confirmation was crucial.
Results:
Our binary regression model consisted of a combination of the following parameters: the number of antibiotics used from patients history, nutritional status (Mini Nutritional Assessment short-form test), presence of pressure ulcers, and occurrence of fever.
Conclusion:
Our logistic regression model may predict mortality in geriatric patients suffering from CDI. This could help improving the therapeutic process.
KEYWORDS:
Clostridium difficile – geriatric patient – binary logistic regression model
Sources
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Geriatrics and Gerontology
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