Biochemical molecular mechanisms of heart failure (Part 2)
Authors:
J. Masopust
Authors‘ workplace:
Přednosta: doc. MUDr. Richard Průša, CSc.
; 2. lékařská fakulta
; Ústav klinické biochemie a patobiochemie
; Univerzita Karlova v Praze
Published in:
Prakt. Lék. 2007; 87(1): 26-31
Category:
Various Specialization
Overview
The article presents an overview of recent findings in the molecular pathobiochemistry of heart failure. In particular, the author describes a role for disturbances in beta-adrenergic signalisation, and the importance both of the renine-angiotensine-aldosterone system and of natriuretic peptides (ANP, BNP). In addition, new methods of laboratory diagnostics and advances in the treatment of heart failure are presented. With its increasing incidence in the population, this clinical syndrome is becoming a greater health and socio-economic problem, and one which requires effective prevention.
Key words:
heart failure, molecular biochemistry, diagnostics and therapy
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2007 Issue 1
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